摘要
目的探讨换血对新生儿血糖及酸碱平衡的影响。方法将137例新生儿分为4组,采用不同红细胞(RBC)与血浆的比例行外周动静脉同步换血,并检测配制好的血液标本和换血前后新生儿的电解质和血糖、血气分析指标及换血前后新生儿的血清总胆红素。结果总的胆红素换出率为(54.36±10.29)%;换血后发生高血糖者126例,血糖由(4.61±1.89)mmol/L上升到(11.38±3.66)mmol/L,差异有统计学意义(t=20.76,P<0.01)。换血前HCO3-(18.42±3.85)mol/L,换血后血清HCO3-(15.21±3.55)mol/L,差异有统计学意义(t=9.42,P<0.01)。结论新生儿换血会导致暂时性的血糖升高和一定程度的HCO3-下降。
Objective To investigate the effect of exchange transfusion on blood glucose and acid-base balance in new borns. Methods One hundred and thirty-seven newborns were divided into four groups. Synchronous peripheral arteriovenous exchange transfusion was performed with different ratios of red blood cells （RBC） and blood plasma. Blood glucose, blood gas, electrolytes and serum total bilirubin were measured before and after blood transfusion. Results After exchange transfu sion, blood glucose was significantly increased from （4.61±1.89） mmol/L to （11.38±3.66） mmol/L （t=20.76, P〈0.01）. HCO3 con centration was significantly decreased from （18.42±3.85） mol/L to （15.21±3.55） mol/L （t=9.42,P〈0.01）. Conclusions Exchange transfusion on newborns temporarily increases the blood glucose and decreases the HCO3 concentration.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2012年第12期1168-1171,共4页
Journal of Clinical Pediatrics
关键词
换血术
血糖
酸碱平衡
新生儿
exchange transfusion
blood glucose
acid-base equilibrium
neonate
