摘要
目的了解镇江市男男性行为者(men who have sex with men,MSM)HIV、梅毒螺旋体血清抗体阳转和队列保持的情况及其影响因素。方法采用前瞻性队列研究,对符合纳入标准的调查对象进行间隔6个月的随访调查,收集社会人口学和行为学信息,并采集血样进行HIV和梅毒螺旋体血清抗体检测。结果共调查MSM456名,HIV和梅毒螺旋体血清抗体阳性率分别为7.7%(95%CI:5.40%～10.51%)和10.5%(95%CI:7.86%～13.71%)。基线建立HIV血清抗体阴性队列421人,6个月随访时队列保持率为27.1%(114/421),HIV和梅毒螺旋体血清抗体阳转率分别为8.24(95%CI:7.58～8.90)/100人年和12.64(95%CI:11.76～13.51)/100人年。比较失访组和在访组基线社会人口学及行为学特征,结果发现两组在婚姻状况、户籍所在地、文化程度、最近6个月寻找性伴场所和与商业性伴发生无保护的肛交等方面差异有统计学意义。结论镇江市MSM的HIV和梅毒螺旋体血清抗体阳转率处于较高水平,针对该人群进行有效的干预已迫在眉睫。
Objective To investigate the incidence of HIV/STD seroconversion,cohort retention and the risk factors among men who have sex with men（MSM） in Zhenjiang City,Jiangsu Province.Methods Prospective cohort study was used to recruited eligible MSM and followed up every 6 months,the demographic and behavior information were collected and blood samples were collected to test HIV and syphilis seroconversion.Results Of 456 MSM investigated at the baseline study,the prevalence of HIV infection and syphilis were 7.7%（95%CI： 5.40%-10.51%） and 10.5%（95%CI： 7.86%-13.71%）,respectively.Of 421 HIV-negative MSM,27.1%（114/421） retained during the 6-month follow up.The incidence of seroconversion for HIV and syphilis were 8.24（95%CI： 7.58-8.90）/100 person years and 12.64（95%CI： 11.76-13.51）/100 person years,respectively.Compared the demographic and behavior characteristic in baseline between defaulters and retesters,the differences in following aspects such as married status,residence status,education level,the way of searching homosexual partners and have unprotected anal intercourse（UAI） with commercial homosexual partners were statistically significant.Conclusions The seroincidences for HIV and syphilis were relatively high among MSM in Zhenjiang,therefore effective HIV/AIDS related prevention and intervention measures targeted MSM are needed.
出处
《中华疾病控制杂志》
CAS
北大核心
2012年第12期1024-1027,共4页
Chinese Journal of Disease Control & Prevention
基金
国家科技重大专项(2012 ZX10001-001
2011ZX10004-902)
江苏省卫生厅医学科研项目(Y201009)
江苏高校优势学科建设工程资助项目(PAPD)
关键词
同性恋
男性
队列研究
随访研究
Homosexuality
male
Cohort studies
Follow-up studies
