摘要
目的 探讨雌激素受体 (ER)对乳腺癌患者预后的影响。方法 对 1993年 1月～ 1998年 8月间经手术治疗的 2 85例乳腺癌患者 ,用免疫组织化学法检测其乳腺标本的ER状况。结果 2 85例乳腺癌ER检测阳性率为 6 8 0 7% ,同期伴腋窝淋巴结转移的乳腺癌 188例的ER阳性率为 6 6 49% ,二者无显著差异 (P <0 0 5 )。术后发生复发转移 11例 ,ER阴性组发生复发转移多于阳性组 ,且易转移至内脏 ,ER阳性和阴性组的复发转移率分别为 1 5 5 %和 8 79%。结论 乳腺癌的ER状况是影响预后的重要因素 ,当ER阴性时 。
Objective To evaluate the influence of estrogen receptor (ER)status on prognosis of breast cancer patients. Methods The ER status was examined by means of immunohistochemistry in 285 breast cancer patients.Results The ER positive rate of 285 breast cancer patients is 68 07% vs 66 49% in 188 patients with positive axillary lymphnodes (P>0 05).The metastasis and recurrence was in 11 cases, and the metastasis of ER negative group was more than ER positive group. The metastasis and recurrence rate of ER negative group and ER positive group was 8 79% and 1 55% respectively. Conclusions The ER status of breast cancer is an important factor for prognosis.
出处
《云南医药》
CAS
2000年第3期195-197,共3页
Medicine and Pharmacy of Yunnan
