摘要
目的:关于长春西汀治疗脑梗死后认知障碍的临床疗效分析。方法:我院于2011年3月-2012年4月收治64例罹患脑梗死者,所筛选的患者均存在梗死后认知障碍的情况,进行随机分组,每组各32例,分别设为研究组和对照组,两组均给予常规神经内科治疗,包括抗血小板、改善脑循环及降低颅内压等,研究组采取长春西汀进行治疗,而对照组采取胞二磷胆碱进行治疗,待2周后,观察两组患者的康复情况。结果:研究组显效率34.4%,有效率53.1%,总有效率为87.4%,对照组显效率18.8%,有效率37.5%,总有效率为56.3%,总有效率比较差异有统计学意义(P<0.05);研究组治疗后MMSE评分明显低于对照组,差异有统计学意义(P<0.05)。结论:长春西汀在治疗脑梗死后认知障碍方面具有明显的优势,能够改善患者的生活质量,同时也可以明显提高患者的肢体活动能力。
Objective：To analyse the clinical efficacy of treatment with vinpocetine for cognitive impairment after cerebral infarction.Methods：64 patients with cerebral infarction and cognitive impairment in our hospital from March 2011 to April 2012 were randomized divided into study group and control group and 32 cases in each group.Patients in the two groups were given conventional neural medical treatment,including anti-platelet,improving cerebral circulation and reducing intracranial pressure,then patients in the study group were treated with vinpocetine,while patients in the control group treated with citicoline.After two weeks,the rehabilitation of patients were observed.Results：In the study group was 34.4%,efficiency rate was 53.1%,and a total effective rate was 87.4%.Excellent efficiency rate in the control group was 18.8%,efficiency rate was 37.5%,and a total effective rate of 56.3%,there was statistically different about total efficiency（P〈0.05）;MMSE score after treatment in the study group was significantly lower than the control group,there was statistically significant（P〈0.05）.Conclusion：Vinpocetine has obvious advantages in the treatment of cerebral infarction with cognitive impairment,can improve the patient＇s quality of life,and also can significantly improve the patient＇s physical activity.
出处
《医学理论与实践》
2012年第24期2997-2998,共2页
The Journal of Medical Theory and Practice
关键词
长春西汀
脑梗死
认知障碍
临床疗效
Vinpocetine
Cerebral infarction
Cognitive impairment
Clinical efficacy
