摘要
无复流现象是指接受直接经皮冠状动脉介入治疗的心肌梗死患者,尽管梗死相关血管开通,但是心肌组织仍然灌注不足,其与不良的临床结果和预后有关。无复流是一个很复杂的现象,有缺血性损伤、远端栓塞、再灌注损伤和个体易患性等多种发病机制。对这些发病机制采取合适的预防和治疗策略有望减少无复流的发生。本文主要阐述了无复流现象的发病机制及其预防和治疗研究进展。
The myocardial no- reflow phenomenon is characterized by a reduced antegrade myocardial blood flow de- spite an open infarct -related artery in patients with myocardial infarction undergoing primary percutaneous coronary intervention. Importantly, no -reflow is known to be associated with unfavorable clinical outcome and prognosis. It is a complex phenomenon and caused by the variable combination of 4 pathogenetic components： distal atherothrombotic embolization, ische- mie injury, reperfusion injury and individual susceptibility. So, appropriate strategies of prevention and treatment are expected to reduce the occurrence of no - reflow. This article mainly explains the research progress of no reflow phenomenon of prevention and treatment.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第36期4160-4162,共3页
Chinese General Practice
关键词
冠状动脉疾病
无复流现象
治疗
Coronary artery disease
No -reflow phenomenon
Therapy
