摘要
目的 探讨鼻咽癌发病与变态反应性疾病的关系。方法 对 49例治疗前鼻咽癌和 5 6例变应性鼻炎的诸临床参数进行探讨 ,测定总IgE、特异性IgE和EB VCA /IgA皮肤过敏原及了解他们的过敏性鼻炎史 ,以 10 0名健康人为对照组。 结果 ①NPC组的总IgE量和特异性IgE阳性率明显低于变应性鼻炎组 (P <0 .0 1) ;②NPC组的过敏性鼻炎史和过敏原阳性率明显低于变应性鼻炎组 (P <0 .0 1) ;③NPC组的EB VCA/IgA滴度明显高于变应性鼻炎组 (P <0 .0 1)。 结论 变应性鼻炎组患NPC的概率很低 ,其机体的免疫状态与肿瘤的发生、发展有密切关系。
Objective To investigate the association between nasopharyngeal carcinoma(NPC) and allergic disease.Methods Total IgE、Specific IgE,EB VCA/IgA detection and skin test were performed in 49 cases of NPC,56 cases of allergic rhinitis and 100 cases of control.Results ①the levels of total IgE and specific IgE in NPC were lower than in allergic rhinitis( P <0.01);②allergic history and positive rates of skin test in NPC were lower than in allergic rhinitis( P <0.01);③the title of EB-VCA/IgA in NPC was higher than in allergic rhinitis( P <0.01).Conclusion Those data suggested that the incidence of NPC might be low in patients with allergic rhinitis,that there is close relationship between immunity and development of tumors.
出处
《实用癌症杂志》
2000年第2期159-161,共3页
The Practical Journal of Cancer
关键词
鼻咽癌
变应性鼻炎
免疫球蛋白E
特异性IGE
Nasopharyngeal carcinoma
Allergic rhinitis
Total IgE
SpecificIgE
EBV VCA/IgA
