摘要
目的:探讨鼻内窥镜下治疗鼻内翻性乳头状瘤的临床治疗效果。方法:选取我院接受治疗的鼻内翻性乳头状瘤患者300例,将所有患者随机分为观察组和对照组2组,每组患者150例。对照组采用传统开放式治疗方案,打开鼻腔后尽量完全切除瘤体及连带组织;观察组采用鼻内窥镜下尽量完全切除瘤体及连带组织。分别在患者术后1、3、6、10个月和1、2年对2组患者的复发例数及复发率进行统计。结果:对2组患者进行跟踪随访,随访率为100%。2组患者术后1个月随访,对照组复发例数为4例(2.7%),观察组复发例数为1例(0.7%),差异无统计学意义,P>0.05;术后3个月对照组复发12例(8.0%),观察组1例(0.7%),差异有统计学意义,P<0.05;术后6个月对照组复发18例(12.0%),观察组3例(2.0%),差异有统计学意义,P<0.05;术后10个月对照组复发18例(12.0%),观察组6例(4.0%),差异有统计学意义,P<0.05;术后1年对照组复发20例(13.3%),观察组6例(4.0%),差异有统计学意义,P<0.05;术后2年对照组复发20例(13.3%),观察组6例(4.0%),差异有统计学意义,P<0.05;随访2年后对照组治愈患者130例(86.7%),观察组144例(96.0%),差异有统计学意义,P<0.05。随访过程中,对照组除20例复发患者外共出现流鼻血患者4例,头痛患者11例;观察组除6例复发患者外共出现轻微头痛患者5例,涕中带血患者2例。结论:应用鼻内镜进行手术治疗鼻内翻性乳头状瘤效果显著,手术方案可行,可以进一步推广应用。
OBJECTIVE： To evaluate the clinical efficacy of the treatment of nasal inverted papilloma in nasal endoscopy. METHODS： Totally 300 patients with nasal inverted papilloma were involved, and all patients were randomly divided into 2 groups, respectively, for the observation group and the control group, each group with 150 cases. Control group were treated using the traditional open-treatment programs, and try to open the nasal complete resection of the tumor and joint tissue; observation group were treated with intranasal endoscopic nasal endoscopic. The 1,3,6,10 months and 1- and 2-year recurrence rate of the two groups were analyzed statistically. RESULTS：Two groups of patients were followed up, and the follow-up rate was 100%. One month after operation, the recurrent cases of control group and observation group were 4（2.7%） and 1（0.7%） respectively （P〉0.05）. Three months after operation, the recurrent cases of control group and observation group were 12（8.0%） and 1（0.7%） respectively （P〈0.05）. Six months after operative, the recurrent cases of control group and observation group were 18（12.0%） and 3（2.0%） respectively （P〈0.05）. Ten month after operation, the recurrent cases of control group and observation group were 18（12.0%） and 6（4.0%） respectively （P〈0.05）. One year after operation, the recurrent cases of control group and observation group were 20 （13. 3%） and 6 （4.0 %） respectively （P（0.05）. Two years after operative, the recure cases of control group and observation group were 130（86.7%） and 144（96.0%） respectively （P〈0.05）. The side effect of control group were nosebleeds（4 cases） and headache （11 cases）, while that of observation group were headache （5 cases） and aldicarb with blood（2 cases）. CONCLUSION：The application of endoscopic sinus surgery for the treatment of nasal inverted papilloma is feasible, and worth to be promoted.
出处
《中华肿瘤防治杂志》
CAS
北大核心
2012年第21期1667-1669,共3页
Chinese Journal of Cancer Prevention and Treatment
关键词
鼻内窥镜
乳头状瘤
临床分析
nasal endoscope
papilloma
clinical analysis
