摘要
目的:探讨根据病机拆分归脾汤治疗心脾两虚型失眠的疗效。方法:将60例心脾两虚型失眠患者随机分为试验组和对照组各30例,试验组采用由归脾汤拆分而成的"寤方"和"寐方",分别于晨起和睡前服用,对照组服用归脾汤治疗。疗程均为2周,观察两组治疗前后失眠症疗效以及反映睡眠质量和日间觉醒状态的匹兹堡睡眠质量指数量表(PSQI)和改良困倦量表(mESS)等疗效指标。结果:试验组和对照组失眠症疗效类似,但试验组能更有效改善睡眠质量,其相关指标明显优于对照组(P<0.05)。结论:根据失眠病机合理拆分方剂较单纯辨证论治指导下的成方能够取得更好的临床疗效。
Objective： To investigate the clinical curative effect of the heart-spleen deficiency insomnia by split Guipi soup according to thepathogenesis. Method： Sixty patients suffering from heart-spleen deficiency type of insomnia were randomly divided into treatment group and control group. The treatment group was given split soups from Guipi soup, namely ＂wu fang＂ and ＂mei fang＂, in the morning and before going to bed accordingly. The control group was given Guipi soup. The duration of treatment lasted 2 weeks. Patients of both groups were measured before and after treatment by the clinical curative effects, Pittsburgh sleep quality index （PSQI） and mESS. Result： After treatment, the clinical curative effects of the two groups were similar, the improvement of the sleep quality in the treatment group was superior to that of the control group, with statistical difference （ P 〈 0.05 ）. Conclusion： The split prescription according to insomnia pathogenesis could gain better clinical efficacy compared to simple syndrome differentiation.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第24期334-336,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
北京市中医药科技项目(JJT2010-12)
关键词
失眠
方剂拆分
心脾两虚
insomnia
split prescription
heart and spleen deficiency syndrome
