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50例膜性肾病临床表现、病理特点与中医证型的相关性分析 被引量:11

Association of Clinical Manifestations and Pathological Features with Traditional Chinese Medicine Syndrome Types in Membranous Nephropathy: An Analysis of 50 Cases
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摘要 目的探讨膜性肾病患者临床表现、病理特点与中医证型的相关性。方法回顾性分析50例膜性肾病患者的相关实验室指标、病理特点及中医证型分布。结果①膜性肾病以肾病综合征、慢性肾炎、高血压、镜下血尿多见,其发生率分别为52.0%、22.0%、26.0%、20.0%。②病理分期以Ⅰ、Ⅱ期多见,各占46.0%、44.0%;肾小球内免疫球蛋白及补体沉积以免疫球蛋白G、免疫球蛋白M、补体C3为主。③中医证型以脾肾阳虚、脾肾气虚型居多,脾肾阳虚型临床表现及病理损害相对较重。结论膜性肾病的临床及病理表现与中医证型有一定的相关性。 Objective To investigate the association of clinical manifestations and pathological features, and traditional Chinese medicine (TCM) syndrome types in membranous nephropathy (MN) patients. Methods Retrospective analysis was performed on the laboratory indices, pathological features, and TCM syndrome types of 50 MN patients. Results Of all patients, 52.0% had nephrotic syndrome, 22.0% had chronic nephritis, 26.0% had hypertension, and 20.0% showed microscopic haematuria. Most cases were classified as pathological stages I and 11 , accounting for 46% and 44%, respectively, and developed glomerular deposition of immunoglobulin G, immunoglobulin M, and complement 3. The main TCM syndromes were spleen-kidney yang deficiency and spleen-kidney qi deficiency, and the patients with spleen- kidney yang deficiency demonstrated relatively severe clinical manifestations and pathological damage. Conclusion The clinical manifestations and pathological features are associated with TCM syndrome types in MN patients.
出处 《安徽中医学院学报》 CAS 2012年第6期32-34,共3页 Journal of Anhui Traditional Chinese Medical College
关键词 膜性肾病 病理 中医证型 membranous nephropathy pathological traditional Chinese medicine syndrome type
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