摘要
胰腺癌是恶性程度最高的消化系统肿瘤,多数患者确诊时肿瘤已发生远处转移,5年存活率仅5%。吉西他滨为治疗晚期胰腺癌的最佳药物,以吉西他滨为基础的疗法广泛用于晚期患者的一线治疗,一旦吉西他滨治疗失败,目前尚缺乏统一的替代方法。晚期胰腺癌的治疗包括联合化疗、区域性动脉灌注、靶向放疗、HIFU、冷冻治疗、PDT等,本文就其研究进展作一综述。
Pancreatic cancer is the most lethal type of digestive cancer with a 5-year survival rate of 5%, most patients had distant metastasis when it was diagnosed. Gemcitabine has been the best medicine in the treatment of advanced pancreatic cancer. While gemcitabine-based regimens are currently accepted as the standard first-line treatment of patients with advanced pancreatic cancer, no consensus has been achieved regarding the second-line treatment setting. Therapy of pancreatic cancer may include combined chemotherapy, regional arterial infusion therapy, targeted radiotherapy, HIFU, cryotherapy, PDT and so forth. This article reviewed the advances in study on therapy of advanced pancreatic cancer.
出处
《胃肠病学》
2012年第11期699-702,共4页
Chinese Journal of Gastroenterology
