摘要
对青霉素类抗生素阿扑西林的红外光谱(IR)、紫外光谱(UV)、核磁共振氢谱(1 HNMR)、氢氢相关谱(1 H-1 H COSY)、核磁共振碳谱(13 C NMR)、DEPT谱、碳氢相关谱(HSQC)、质谱(MS)进行了解析,对其所有的NMR谱信号进行了归属,同时讨论了质谱的主要碎片离子的可能的裂解方式和红外特征吸收峰所对应的官能团的振动形式.通过多种波谱技术确证了阿扑西林的结构.
The infrared spectrum, ultraviolet spectrum, nuclear magnetic resonance spectra and mass spectra of aspoxicillin, a semi-synthetic penicillin, were collected and interpreted. All the NMR signals were assigned. Based on the mass spectral data, the possible fragmentation pathways were discussed. The infrared spectrum was used to analyze the types of vibration of the functional groups in this compound. The structure of the compound was determined.
出处
《波谱学杂志》
CAS
CSCD
北大核心
2012年第4期582-589,共8页
Chinese Journal of Magnetic Resonance
基金
科技型中小企业技术创新基金资助项目(09C26211102765)
关键词
核磁共振(NMR)
结构确证
阿扑西林
红外光谱
紫外光谱
质谱
NMR, structure elucidation, aspoxicillin, infrared spectroscopy, ultraviolet spectroscopy, mass spectroscopy
