摘要
目的:观察Ahmed青光眼阀(Ahmed glaucoma valve,AGV)植入术中应用丝裂霉素C(MMC)联合视网膜光凝治疗新生血管性青光眼(neovascular glaucoma,NVG)的临床疗效。方法:回顾性分析行AGV植入术中应用MMC联合视网膜光凝术治疗的41例41眼NVG患者临床资料,观察患者眼压变化、视力变化、手术成功率及并发症情况。结果:患者术前平均眼压49.8±4.3mmHg,术后1,3,6,12mo分别为18.30±4.50,19.40±5.37,18.45±4.60,17.85±3.66mmHg。末次随访平均眼压20.25±4.2mmHg,与术前眼压相比差异均具有统计学意义(P<0.05)。随访6～24mo,手术成功率为93%,其中完全成功36眼(88%),部分成功2眼(5%),失败3眼(7%)。手术前后视力差异无统计学意义(P>0.05)。术后常见并发症为术后早期低眼压4眼(10%);术后浅前房1眼(2%);前房少量出血3眼(7%);引流管内口阻塞1眼(2%)。结论:AGV植入术中应用MMC联合视网膜光凝治疗NVG临床疗效显著,可以有效降低NVG患者的眼压。
AIM：To investigate the clinical efficacy of Ahmed glaucoma valve implantation with mitomycin C（MMC） combined with retinal photocoagulation for treatment of neovascular glaucoma（NVG）.METHODS：The medical records of 41 cases 41 eyes of NVG who underwent Ahmed glaucoma valve implantation with MMC combined with retinal photocoagulation were retrospectively analyzed, including intraocular pressure （IOP）, visual acuity, the operative success rate and surgery complications.RESULTS：The average IOP postoperatively all had statistical difference compared with preoperative IOP （all P0.05）. The operative successful rate was 93%, in which 36 eyes（88%） with complete success, 2 eyes （5%） with success at certain condition and 3 eyes （7%） with failure. The difference of visual acuity was not significant（P0.05）. The complication after the operation included early hypotony in 4 eyes （10%）, postoperative shallow anterior chamber in 1 eye （2%）, hyphema in 3 eyes （7%） and tube occlusion in 1 eye （2%）.CONCLUSION：Ahmed glaucoma valve implantation with MMC combined with retinal photocoagulation is a safe and effective therapy to decrease the IOP of NVG.
出处
《国际眼科杂志》
CAS
2012年第12期2358-2360,共3页
International Eye Science
