摘要
目的探讨神经阻滞治疗对老年带状疱疹患者的临床疗效及其对T淋巴细胞亚群的影响。方法两组病例入院后进行VAS评分并查T淋巴细胞亚群,经4次神经阻滞治疗之后,再次对患者进行VAS评分并查T淋巴细胞亚群。结果经神经阻滞治疗后,实验组患者VAS评分明显下降(P<0.01),治疗前实验组与对照组相比,T淋巴细胞亚群中CD4+,CD4+/CD8+,CD3+/DR-明显较少(P<0.05)。治疗后实验组与对照组相比CD4+、CD4+/CD8+明显减少(P<0.05),CD8+明显增多(P<0.05)。实验组治疗前后比较CD4+明显减少(P<0.05)。结论带状疱疹老年患者T淋巴细胞亚群免疫功能明显下降,神经阻滞治疗对老年带状疱疹患者效果显著,对提高患者T淋巴细胞亚群功能无明显作用。
Objective To observe the effects of neural blockade on the elder herpes zoster（HZ） and T-lymphocyte subsets.Methods All the patients were treated with nerve block,the pain were evaluated by visual analogue scale（VAS） and T-lymphocyte subsets was determined before treatment and after 4 treatments.Results After treatment,all the score of VAS decreased significantly comparing with that before treatment（P0.01）.CD4＋、CD4＋/CD8＋、 CD3＋/ DR-of experimental group were significant lower than that of control groups（P0.05）.compared with the control group,CD4＋ 、CD4＋/CD8＋were decreased and CD8＋ was increased after treatment（P 0.05）.CD4＋ was significantly reduced after treatment in the experimental group（P 0.05）.Conclusion The T-lymphocyte subsets immune function of the elder HZ patient is lower than other patients in the same age;neural blockade is effective on HZ,but no significant influence on T-lymphocyte subsets immune function.
出处
《中国医药指南》
2012年第31期10-12,共3页
Guide of China Medicine
基金
青岛市科技局资助课题10-3-3-4-10-nsh
青岛市市南区资助课题2009-5-31-GG
