摘要
目的探讨三维超声重建法计算体积的准确性及影响因素。方法制作A、B两组球囊模型,每组各19只球囊,球囊内分别两两对应地充填不同容量规格的生理盐水和SonoVue超声造影微泡剂溶液,封闭后包埋于超声耦合剂中。使用Voluson-E8RAB2-5-D腹部三维探头对各球囊进行三维扫查,获取初始三维数据。运用VOCAL方法计算各球囊体积;运用三维多平面成像技术获取各球囊三个相互垂直的最大二维切面,测量各切面的最大径线,引用椭球体体积公式计算各球囊的体积。结果各球囊均获得相应的三维法体积值和公式法体积值。三维法体积值与实际容量值高度接近,尤以A组贴合更佳;公式法体积值均明显大于实际容量值,尤以B组为甚。二维公式法体积的误差大于三维法体积(t=5.4913,P<0.001)。A、B两组球囊的三维法体积值平均相差(12.33±7.67)ml(t=7.008,P<0.001),B组体积值大于A组。结论三维重建VOCAL法计算体积时比二维径线公式法准确,贴近真实;采用三维法计算体积时强调要正确和准确地勾画拟测目标的边界。
Objective To investigate the difference of volume calculation accuracy between three-dimensional volumetry and two dimensional formulization by using ultrasonography on experimental models. Methods A pare of 19 balloon mod- els were set up in group A and group B. The balloons were filled in 19 different matching scales of amount, with saline in group A and with SonoVue micro-bubbles solution in group B. They were sealed and embedded in ultrasound gel container for ultrasound scanning. For three-dimensional data acquisition, an RAB 2-5-D probe available on Voluson-E8 ultrasound set （GE medical Co. , America） was used. The intrinsic VOCAL technique was applied for processing the volume data in a subtle rotation step of 6 degrees to yield the volume value of each balloon （i. e. 3D-volume）, and meanwhile multi-planar technique was used to produce three perpendicular planes for maximum length determinations. The three lengths for each balloon were citated for volume calculation based on spheroid formula （i. e. 2D-volume）. Results 3D-volume and 2D-vol- ume were successfully calculated concomitantly for each balloon. 3D-volume value was highly close to the actual amount of filling liquid in each balloon, with superiority in group A. 2D-volume value was biased in over-estimation to the actual a- mount of filling liquid in each balloon, especially in group B. The bias of 2D volumetry was greater than that of 3D volum- etry in a significant statistical difference （ t = 5. 4913, P 〈0. 001）. 3D volume values between group A and group B were proved in a mean difference of （12.33 ±7.67） ml （ t =7. 008, P 〈0. 001） with the values greater in group B. Conclusion 3D-volumetry with VOCAL software can help achieve volumes much closer to the actual volume of object than 2D-volume- try. Proper and precise delineation along the inner border of region of interest is essential and critical while performing VOCAL processing.
出处
《医学影像学杂志》
2012年第11期1951-1955,共5页
Journal of Medical Imaging
关键词
体积
三维重建体积测定法
椭球体公式体积计算法
超声成像
实验研究
Volume
Three dimensional reconstruction volumetry
Spheroid formula volume calculation
Ultrasonogra-phy
Experimental study
