摘要
高能饲料诱导大鼠肥胖的动态过程中 ,用放射免疫分析方法测定大鼠血清中胰岛素 (lnsulin)及生长激素 (Growthhomorn)水平。采用westhemblot技术检测大鼠血清中瘦素(Leptin)的水平。结果发现随大鼠体重 (BW )增加 ,瘦素水平、胰岛素水平增加 ,而生长激素水平随大鼠体重增加而下降。说明瘦素与肥胖的发生发展存在一定的关系 ,且与胰岛素、生长激素之间的变化规律存在相互作用 。
To study the change of leptin with westhern blot and detect the insulin (INS) and growth hormone (GH) in serum using radioimmunoassay during high-calorie diet induce rats obesity.The results show leptin and INS were rised with increased bodyweigh (BW) of rats, but the GH was declined with the increased BW. It suggest that there are relations between obesity and leptin and exist mutual action mechanism among leptin and insulin and GH during inducing rats obesity.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2000年第4期289-290,共2页
Chinese Journal of Public Health
基金
国家自然科学基金资助
关键词
肥胖
瘦素
胰岛素
生长激素
Obesity Leptin Insulin Growth hormone
