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厄贝沙坦氢氯噻嗪片治疗轻中度高血压病疗效观察

Observation on Clinical Efficacy of Irbesartan Hydrochlorothiazide Tablets for the Treatment of Patients with Mild-to-moderate Hypertension
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摘要 【目的】探讨厄贝沙坦氢氯噻嗪片治疗轻中度高血压病患者的疗效。【方法】将136例轻中度高血压病患者随机分为两组,观察组(68例)服用厄贝沙坦氢氯噻嗪片治疗,对照组(68例)服用厄贝沙坦片治疗,均治疗8周,对比分析两组患者的疗效及不良反应。【结果】观察组总有效率为97.1%,明显高于对照组的77.9%,差异有显著性(P〈0.05),两组患者不良反应发生率相比较差异无显著性(P〉0.05)。【结论】厄贝沙坦氢氯噻嗪片治疗轻中度高血压痛患者具有疗效确切、不良反应发生率低等优点。 [Objective] To explore the clinical efficacy of irbesartan hydrochlorothiazide tablets for the treatment of patients with mild-to-moderate hypertension. [Methods] Totally 136 patients with mild-to-moderate hypertension were divided into 2 groups randomly. The observation group( n= 68) received irbesartan hydrochlorothiazide tablets, while control group( n = 68) was given irbesartan hydrochlorothiazide tablets. All patients were treated for 8 weeks. The efficacy and incidence rate of adverse reactions were compared between two groups. [Results] The total effective rate in observation group was 97.1%, which was obviously higher that in control group, and there was significant difference( P〈0.05). There was no significantly difference in the incidence rate of adverse reactions between 2 groups( P〉0. 05). [Conclusion] Irbesartan hydrochlorothiazide tablets for the treatment of patients with mild-to-moderate hypertension has advantages such as certain efficacy and low incidence rate of adverse reactions.
作者 洪英清
出处 《医学临床研究》 CAS 2012年第10期1933-1934,共2页 Journal of Clinical Research
关键词 高血压 药物疗法 受体 血管紧张素 投药和剂量 氢氯噻嗪 投药和剂量 Hypertension/DT receptors, angiotensin/AD hydrochlorothiazide/AD
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