摘要
【目的】探讨不同手术方法治疗高危重度前列腺增生(BPH)患者的疗效。【方法】92例高危重度BPH患者分为三组:观察组(n=32),行双侧髂内动脉介入栓塞联合经尿道前列腺电切术(TURP);TURP组(n=30);经尿道前列腺钬激光剜除术(HoLEP)组(Ⅺ一30)。比较三组的治疗效果。【结果】术中实施手术时间观察组少于其他两组(均P〈0.01);术中出血量观察组与HoLEP组无显著性差异(P〉0.05),但少于TURP组(P〈0.01);三组手术切除前列腺重量无显著性差异(P〉0.05);切除速度观察组快于TURP组及HoLEP组(均P〈0.01)。术后膀胱冲洗时间观察组介于HoLEP组与TURP组之间,TURP组最长,HoLEP组时间最短(均P〈0.01)。术后剩余尿量(PRV)迅速下降,并随术后恢复时间增长,PRV逐渐减少,本组各时间段(术前,拔管后,术后3个月)两两比较均有差异(P〈0.01),而术后三组患者PRV比较无显著性差异(P〉0.05)。术后至术后3个月Qmax评分随术后恢复时间增长而逐渐增加,本组各时间段指标比较均有显著性差异(P〈0.01),三组间比较无显著性差异(P〉0.05)。【结论】双侧髂内动脉介入栓塞联合TURP治疗与TURP及HoLEP有相同的近期临床疗效,术中手术时间短,切除速度快,出血量少,推荐对高危重度BPH患者常规术前行双侧髂内动脉栓塞治疗。
[Objective]To explore the efficacy of different surgical methods for the treatment of high-risk and severe benign prostatic hyperplasia(BPH). [Methods] Totally 92 patients with high-risk and severe BPH were divided into the observation group( n = 32) undergoing bilateral internal iliac artery transcatheter embolization combined with transurethral electroresection of prostate(TURP), TURP group( n = 30) and holmium laser enucleation of the prostate(HoLEP) group( n = 30). The therapeutic effects were compared among 3 groups. [Results]The operation time in the observation group was less than that in other two groups(all P〈0.01). There was no significant difference in blood loss volume between observation group and HoLEP group, but blood loss volume in observation group was less than that in TURP group( P〈0. 01). There was no sig- nificant difference in resected prostate weight among 3 groups( P 〉0.05). The resection speed in observation group was faster than that in TURP group and HoLEP group(all P〈0.01). The bladder washing time in observation group after operation was between HoLEP group and TURP group, and that in HoLEP group was the shortest(all P〈0.01). Postoperative residual urine(PRV) declined rapidly and decreased gradually with the increasing of postoperative recovery time, and there were significant differences between 2 groups at every time( P〈0.01). There was no significant difference in PRV after operation among 3 groups( P〉0.05). Qmax score after operation and 3 months after operation increased progressively with the increasing of postop-erative recovery time, and there were significant differences among different time( P〈0.01), but there was no significant difference among 3 groups( P 〉0.05). [Conclusion]Clinical efficacy of bilateral internal iliac ar- tery transcatheter embolization combined with TURP is similar to TURP or HoLEP. Bilateral internal iliac artery transcatheter embolization has short operation time, rapid
出处
《医学临床研究》
CAS
2012年第10期1904-1906,共3页
Journal of Clinical Research