摘要
目的探讨阿托伐他汀在绝经后骨质疏松症患者中的作用。方法将80例绝经后骨质疏松患者随机分为A1组(钙、活性维生素D3、阿托伐他汀治疗组)和A2组(钙、活性维生素D3治疗组),共6个月,选择30例正常对照组的腰椎、股骨颈的骨密度及血β-胶原、骨钙素作为对照。结果骨质疏松组治疗前与正常对照组相比,β-胶原、骨钙素、腰椎、股骨颈骨密度差异明显(P<0.01),A1与A2组治疗前比较无统计学差异,A1组治疗前后比较差异明显(P<0.05),A2组治疗前后骨钙素无明显差异(P>0.05),β-胶原、腰椎、股骨颈治疗前后差异明显(P<0.05)。结论阿托伐他汀在骨质疏松中发挥一定的作用。
objective To explore the role of atorvastatin in postmenopausal osteoprosis.Methods Dected the bone mineral density of neck and lumbar spine and blood levels of β-crosslaps and osteocalcin concentration. Patients randomLy received caltrate and rocaltrol and atorvastatin or received caltrate and rocaltrol for six moons.Results Before treatment the levels β-crosslaps and osteocalcin concentration all significantly change,after treatment,the atorvastatin group significantly changed.Conclusion Atorvastatin have some effection in postmenopausal osteoprosis.
出处
《当代医学》
2012年第34期129-130,共2页
Contemporary Medicine
