摘要
目的分析探讨胃镜下黏膜剥离术(endoscopic submucosal dissection,ESD)在诊治早期食管癌和癌前病变中的临床应用价值。方法回顾分析胃镜下行ESD治疗的18例患者的临床资料。结果 17例一次性完全切除,ESD剥离病变成功率94.44%(17/18);所有剥离病变全部得到病理确诊,基底和切缘未见病变累及;ESD手术时间(自黏膜下注射至完整剥离病变)35～150min,平均65 min;术后未发生出血、穿孔等并发症;术后随访3～24个月(平均14个月),创面完全愈合,无1例病变残留和复发;术前病理与术后病理对照相符者13例,占72.22%。结论 ESD操作安全,创伤少,恢复快,在早期食管癌和癌前病变的诊疗中值得推广。
Objective To assess the clinical application value of endoscopic submucosal dissection （ESD） for early esophageal carcinomas and precancerous lesions. Methods Retrospective analysis gastroscope downside ESD treatment of 18 patients＇ clinical data. Results 17 cases one-time complete excision, ESD stripping lesions rate was 94.44% （17/18）. All stripping get pathological lesions diagnosis, the basal and the cut edge were not involved; ESD operation time were from 35 to 150 min, average of 65 min. No postoperative complications such as hemorrhage perforation. Follow-up of 3 -24 months （mean, 14 months） , the wound healed fully, without residual lesions and recurrence. Preoperative and postoperative pathology is accord in 13 patients （72.22%）. Conclusion ESD is safe, has less trauma, recover quickly, which worth promoting in the diagnosis and treatment of early esophageal cancer and precancerous lesions.
出处
《胃肠病学和肝病学杂志》
CAS
2012年第11期1051-1053,共3页
Chinese Journal of Gastroenterology and Hepatology
关键词
内镜黏膜下剥离术
早期食管癌
癌前病变
Endoscopic submucosal dissection
Early esophageal
Precancerous lesions
