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高同型半胱氨酸与老年人静脉血栓的关系

Association between homocysteine and venous thrombosis of the elderly
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摘要 目的:讨论高同型半胱氨酸水平增高与老年人静脉血栓栓塞症的关系。方法:对19例确诊有下肢静脉血栓的老年患者,用高效液相色谱法测定血浆同型半胱氨酸的水平,设年龄、性别匹配的正常对照组20例。结果:下肢静脉血栓组的同型半胱氨酸水平高于正常对照组(P<0.05),静脉血栓患者中34.1%血浆同型半胱氨酸水平升高,高同型半胱氨酸使静脉血栓发生的相对危险性增加2.44倍,且随着年龄增长呈指数增加,故老龄可作为静脉血栓栓塞的独立危险因素。结论:老年人血浆中同型半胱氨酸的升高是静脉血栓形成的一个危险因素。 Objective To discuss the association between the increased homocysteine levels and venous thromboembolism of the elderly. Methods The plasma homocysteine levels of deep vein thrombosis elderly patients (19 cases) and normal control group (20 cases) were determined by high performance liquid chromatography. Results The homocysteine levels of deep vein thrombosis group higher than the normal control group (P〈0.05), 34.1% of the venous thrombosis patients have increased plasma homocysteine levels, and the relative risk of venous thrombosis increased 2.44 times. Meanwhile, the relative risk of venous thrombosis increases exponentially with age, so aging is an independent risk factor for venous thromboembolism. Conclusion The increased elderly plasma homocysteine is a risk factor for venous thrombosis.
出处 《中国美容医学》 CAS 2012年第10X期112-113,共2页 Chinese Journal of Aesthetic Medicine
关键词 老年人 同型半胱氨酸 静脉血栓 elderly, homocysteine, vein thrombosis.
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