摘要
目的了解本地区泌尿生殖道支原体感染及耐药情况。为临床合理用药提供依据。方法对2007年1月至2011年12月间的893例疑似泌尿生殖道感染患者的支原体培养及体外药敏实验结果进行回顾性分析。结果893例受检标本中有531例支原体培养呈阳性，感染率为59．46％，男性标本的阳性率为37．62％，女性标本的阳性率为62．24％，女性感染率明显高于男性（P〈0．01）。解脲脲原体、人型支原体以及两者合并感染的阳性率分别为54．75％、1．01％和3．70％。支原体感染高发年龄集中在20～40岁。药敏结果显示9种抗菌药物的敏感性由强到弱依次为原始霉素（99．06％）、强力霉素（96．99％）、交沙霉素f95．29％）、四环素f92．47％）、克拉霉素（79．28％）、阿奇霉素（62．52％）、红霉素（54．80％）、氧氟沙~z（19．78％）、环丙沙星（9．98％）。结论本地区支原体感染率较高，以Uu为主。该地区治疗泌尿生殖道支原体感染宜选择原始霉素、强力霉素、交沙霉素、四环素。
Objective To investigate the infection status and drug resistance of mycoplasma isolated from urogenital tract infection cases, so as to provide guidance for rational clinical treatment. Methods The specimens of 893 cases were collected from Jan 2007 to Dec 2011. The results of mycoplasma cultivation and susceptibility test were analyzed retrospectively. Results Among all the 893 cases,531 were positive（59.46%）. Among 101 males,38 were positive （37.62%） . Among 792 females,493 were positive （62.24%）. Females were more apt to be infected than males according to the statistics （P〈0.01）. The positive rates of Uu infection,Mh infection,both Uu and Mh infection were 54.75%, 1.01%and3.70% respectively. Most patients with mycop;asma infection were in an age range of 20 to 40 years old. The order of drug sensitivity for mycoplasma was Pristinamycin （99.06%）, Doxycycline （96.99%）, Josamycin （95.29%）,Tetracycline （92.47%）, Clarithromycin （79.28%）,Azithromycin（62.52%）,Erythromycin（54.80%）,Ofloxacin（19.78%） and Ciprofloxacin （9.98%）. Conclusion The infection rate of mycoplasma in the patients with urogenital tract infection in this area is at a high level,especially the Uu infection. To cure urogenital tract mycoplasma infection,pristinamycin,doxycycline, josamycin and tetracycline should be chose as the main drugs.
出处
《实验与检验医学》
CAS
2012年第5期467-469,共3页
Experimental and Laboratory Medicine
关键词
解脲脲原体
人型支原体
药敏试验
Ureaplasma urealyticum
Mycoplama hominis
Drug resistance
