摘要
目的:分析慢性乙型肝炎和肝炎后肝硬化在中医临床信息表达上的差异性,探寻肝炎后肝硬化的中医证候病机特点。方法:运用频次统计和logistic回归分析方法对1037例慢性乙型肝炎(787例)和肝炎后肝硬化(250例)患者的中医常见症状(体征)进行分析,找出与肝炎后肝硬化的正相关因素。结果:在纳入分析的43项常见中医症状或体征中,ORj值大于1的有下肢沉重、肝掌、夜尿频多、下肢浮肿、面色晦暗、肌肤甲错和蜘蛛痣(分别为1.4、1.6、1.7、1.8、2.1、2.7和8.0),此7项症状或体征的出现或加重与肝硬化的发生密切相关。结论:下肢浮肿、夜尿频多、肝掌、蜘蛛痣、肌肤甲错和面色晦暗为慢性肝炎向肝硬化转化的主要标志,正虚血瘀、水湿内停为肝炎后肝硬化中医主要证候病机特点。
Objective Analyse the otherness of chronic hepatitis b and hepatitis liver cirrhosis in Chinese medicine clinical information expression,explore the posthepatitic cirrhosis of TCM syndrome pathogenesis characteristics.Method Use frequency statistics and logistic regression analysis method analyse 1037 cases of chronic hepatitis B（787 cases） and posthepatitic cirrhosis（250 cases） of patients with TCM clinical symptoms and B ultrasonic examination results,find out the posthepatitic cirrhosis is relevant factors.Result In into the analysis of the common TCM signs or symptoms,which ORj value greater than 1 are Heaviness of lower limbs Liver palms Noctural polyuria Edema of lower limbs Opaque complexion Spider（respectively 1.4、1.6、1.7、1.8、2.1、2.7、8.0）,The seven signs or symptoms appear or worsen and liver cirrhosis of the occurrence of closely related.Conclusion TCM pathogenesis of posthepatitic cirrhosis characteristics is ZhengQi asthenia ShiXie agglomeration.In the clinical symptoms Lower limb swelling Nocturia Liver palm Spider Nevus squamousanddryskin complexion dull is the main sign for chronic hepatitis into cirrhosis.
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2012年第11期1227-1229,共3页
JOURNAL OF BASIC CHINESE MEDICINE
基金
中医药防治病毒性肝炎的临床科研基地建设(2009ZX10005-017)
