摘要
目的:探讨代谢综合征在老年良性前列腺患者病程中的作用。方法:选择湖南师范大学第二附属医院老年病科2010年1月至2012年1月门诊及住院的男性良性前列腺增生合并代谢综合征患者88例,同时选择同期的单纯良性前列腺增生患者90例,分析体重指数、血压、腰围、空腹血糖、胰岛素抵抗指数、总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白、前列腺特异性抗原等对及前列腺体积的影响。结果:BPH合并MS组PV为(39.7±21.1)mL,明显高于单纯BPH组,且PV与BMI、收缩压、空腹血糖、PSA呈正相关,与高密度脂蛋白呈负相关。结论:BPH与MS具有相关性,BMI、收缩压、PSA、FBG、低密度脂蛋白是BPH发生发展的危险因素。
ABSTRACT Objective： To explore the effect of metabolic syndrome （MS） on the occurrence and development of benign prostatic hyperplasia （BPH）. Methods： 88 male BPH patients with MS and 90 male BPH patients without MS were enrolled from January 2010 to January 2012 in the department of geriatrics of the Second-affiliated Hospital of Hunan normal university.The effects of metabolic indexes,including body mass index（BMI）, blood pressnre（BP）, wasit, fasting blood glucose, insuline resistance index（HOMA-IR）, total cholesterol（TC）, triglycerides（TG）, high-density lipoprotein cholesterol（HDL-C）, low-density lipoprotein cholesterol（LDL-C）, and PSA （prostate specific antigen） on PV. were performed. Results： PV in patients with MS was significantly larger than in patients without MS. PV were positively correlated with BMI, FBG, SBP（systolic blood pressure）, but negatively correlated with HDL-C. Conclusion： BPH is closely correlated with PAS, BMI, FEG, SBP, and low HDL-C may play roles in the pathagenesis of benign prostatic hyperplasia. Key Words： Metabolic syndrome（MS）; Benign prostatic hyperplasia（BPH）
出处
《现代生物医学进展》
CAS
2012年第29期5695-5697,共3页
Progress in Modern Biomedicine
关键词
良性前列腺增生
代谢综合征
Metabolic syndrome（MS）
Benign prostatic hyperplasia（BPH）
