摘要
目的评价天津市20岁以上人群乙型病毒性肝炎(简称乙肝)的控制效果,为乙肝的防治提供科学依据。方法对2005和2010年天津市20岁以上成人急性乙肝报告的发病率,以及1992和2010年天津市疾病预防控制中心乙肝血清学抽样监测结果进行评价。结果天津市2010年共监测20岁以上成人3 198人,乙肝病毒表面抗原、表面抗原抗体和核心抗原抗体阳性率分别为3.28%、40.68%和13.13%;各年龄组间表面抗原阳性率以50～59岁组最高(4.56%),20～29岁组表面抗原抗体阳性率(48.23%)高于其他年龄组;同1992年监测结果相比,表面抗原阳性率下降39.82%(2=8.16,P=0.004),表面抗原抗体阳性率上升25.44%(2=17.79,P<0.001)。天津市2010年20岁以上人群急性乙肝报告发病率为3.06/10万,较2005年的7.26/10万下降57.85%(2=160.66,P<0.001)。结论发病率和血清学监测结果均证实天津市20岁以上人群乙肝控制效果明显。
Objective To evaluate the control effect of hepatitis B in Tianjin residents aged over 20 in order to provide scientifc evidence for hepatitis B control and prevention. Methods The report incidence of acute hepatitis B in people aged over 20 in 2005 and 2010, and the result of seroepidemiology survey by Tianjin center for disease control and prevention in 2010 were used as materials. Results In the total 3 198 seroepidemiology samples of 〉 20 adults, the posi- tive rate of hepatitis B virus （HBV） surface antigen （HBsAg）, antibody to HBsAg （anti-HBs） and antibody to HBV core antigen （anti-HBc） was 3.28%, 40.68% and 13.13%, respectively. The highest positive rate of HBsAg was 4.56% in 50-59 group, while the 20-29 group had the highest positive rate of anti-HBs （48.23%）. Compared with the result in 1992, the positive rate of HBsAg was declined by 39.82% （x^2 =8.16, P=0.004）, and the positive rate of anti-HBs was risen by 25.44% （x^2 = 17.79, P〈0.001 ）. The incidence of acute hepatitis B was 3.06 per 100 000 in people aged over 20 in Tianjin in 2010, which was declircd by 57.85% compared with the result in 2005 （7.26/100 000） （x^2 = 160.66, P〈0. 001 ）. Conclusions The incidence of hepatitis B and result of seroepidemiology have confirmed that the control effect of hepatitis B in Tianjin residents aged over 20 was obvious.
出处
《中华疾病控制杂志》
CAS
北大核心
2012年第11期962-964,共3页
Chinese Journal of Disease Control & Prevention
