摘要
目的比较颅骨钻孔尿激酶溶解引流术与小骨窗开颅血肿清除术治疗高血压脑出血临床效果。方法选择我院2009年5月～2011年4月收治的高血压脑出血(HICH)患者68例,随机分为观察组与对照组,每组各34例。观察组给予颅骨钻孔尿激酶溶解引流术治疗,对照组给予小骨窗开颅血肿清除术治疗,对比两组患者手术时间、住院时间、再出血率及近、远期疗效。结果观察组手术时间及住院时间均显著短于对照组,差异有高度统计学意义(均P<0.01);术后再出血发生率差异无统计学意义(P>0.05);观察组近期总有效率高于对照组,差异有统计学意义(P<0.05);远期恢复良好率显著高于对照组,差异有高度统计学意义(P<0.01)。结论颅骨钻孔尿激酶溶解引流术治疗HICH显著优于小骨窗开颅血肿清除术,安全可靠,值得临床推广。
Objective To contrast the clinical efficacy of the application of skull drill drainage-urokinase perfusion and small bone flap craniotomy for removing the hematoma in patients with hypertensive cerebral hemorrhage（HICH）.Methods 68 patients with HICH in our hospital from May 2009 to April 2011 were randomly divided into observation group（n=34） and control group（n=34）,the observation group was treated with skull drill drainage-Urokinase perfusion,and the control group was treated with small bone flap craniotomy,then the operating time,hospital stays,rehaemorrhagia rate,short term effects and long-term effects were contrasted between the two groups.Results Operating time and hospital stays in observation group were significantly shorter than that in control group,the differences were all statistically significant（all P0.01）,the difference of rehaemorrhagia rate was not significantly significant（P0.05）;the difference of short term effect between the two groups was significantly significant（P0.05）,the difference of long-term effect between the two groups was significantly significant（P0.01）.Conclusion The application of skull drill drainage-urokinase perfusion has a better effects for removing the hematoma in HICH than small bone flap craniotomy and it is safe,reliable and worthy of clinical application.
出处
《中国医药导报》
CAS
2012年第29期70-71,共2页
China Medical Herald
