摘要
目的:探讨伴性索分化的低度恶性子宫内膜间质肉瘤的临床病理特征、生物学行为及预后。方法:对1例伴性索分化的低度恶性子宫内膜间质肉瘤的临床、病理和免疫学表型进行观察、分析及文献复习。结果:结合组织学特点及免疫组化结果,诊断为伴性索分化的低度恶性子宫内膜间质肉瘤。结论:伴性索分化的低度恶性子宫内膜间质肉瘤是一种极其少见的现象。其诊断依赖于组织病理学、免疫组化,并须结合其临床资料。
Objective:To investigate the clinicopathological features of uterine tumor resembling ovarian sex-cold tumor(UTROSCT)and its behaviour and prognosis.Methods: The clinical data was analysed of one case of UTROSCT with review of the literature.Results: Microscopically,the tumor cells were arranged in sheets with formation of small cords,trabeculaes,or solid tubules structures.The tumor cells grew in diffusely infiltrative fashion that invaded the myometrium.Immunohistochemically,the cells showed positive for CD10,ER.Ki-67 labelling index was about 10%.But the cells showed negative for inhibin,MelanA,PAX-5,Desmin and SMA.Conclusion: UTROSCT is a very rare tumor,definite diagnosis should be based on the histopathological and immunohistochemical features.Its clinical manifestation should also be taken into account.
出处
《现代肿瘤医学》
CAS
2012年第11期2408-2409,共2页
Journal of Modern Oncology
关键词
低度恶性
子宫内膜间质肉瘤
性索分化
病理学
免疫组织化学
low-grade malignant potential
endometrial stromal
sex cord-like differentiation
pathology
immunohistochemistry