摘要
目的回顾性分析内镜黏膜剥离术(endoscopic submucosal dissection,ESD)对大肠侧向发育型肿瘤(lateralspreading tumor,LST)的治疗结果。方法回顾性分析2009年5月至2012年3月间我科收治的41例LST患者行ESD治疗的手术操作时间、切除病灶直径、整切率、术中术后并发症、复发率及治愈率。结果 41例LST行ESD治疗,手术操作时间:10～115(63.2±24.3)min,病灶直径:1.2～12(4.0±2.7)cm,整切38例(38/41,92.3%),术中穿孔1例(1/41,2.4%),术后穿孔1例(1/41,2.4%),术后出血2例(2/41,4.8%),术后直肠狭窄1例(1/41,2.4%)。随访时间1～34(12.0±9.7)个月,残余灶1例,复发2例(2/41,4.9%),治愈40例(40/41,97.6%)。结论 ESD治疗LST的操作时间短、整切率高、复发率低。
Objective To evaluate the therapeutic effect of endoscopic submucosal dissection （ESD） for 41 cases suffering from colorectal laterally spreading tumor （CLST）. Methods A retrospective study was performed in 41 CLST cases who operated with ESD in our endoscopic center from May 2009 to March 2012. Procedure time, tumor diameter, en bloc resection rate, residue rate, recurrent rate, cure rate and associated complications after ESD were evaluated. Results Among the 41 CLST cases receiving ESD, procedure time ranged from 10 to 115 min （ mean 63.2 ± 24.3 ） , lesions diameter from 1.2 to 12 cm （ mean 4.0 ± 2.7 ） , and en bloc rate was 92, 3% （38/41）, intraoperative perforation 2.4% （ 1/41 ）, postoperative perforation 2.4% （ 1/41 ）, postoperative bleeding 4.8% （2/41）, postoperative rectum stricture 2.4% （ 1/41 ）, and residue rate 2.4% （ 1/41 ）. During the follow-up of 1 to 34 month （mean 12.0 ±9.7）, recurrent rate was 4.9% （2/41）, and cure rate was 95.1% （39/41）. Conclusion ESD has a good therapeutic effect for CLST, with short procedure time, high en bloc resection and low recurrent rate.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
2012年第21期2200-2203,共4页
Journal of Third Military Medical University
关键词
内镜黏膜剥离术
大肠侧向发育型肿瘤
endoscopic submucosal dissection
colorectal lateral spreading tumor .,
