摘要
目的探讨利用不同b值和测量位置得到的表观扩散系数(ADC)值及灌注ADC值在肝脏良恶性肿瘤鉴别诊断中的价值。方法对120例肝脏肿瘤进行常规MRI平扫和扩散加权成像扫描,其中48例肝脏肿瘤同时进行了多期增强扫描。采用表观扩散系数(b值)分别为0s/mm2和1000s/mm2,测量病变整体、边缘及中心的表面扩散系数(ADC)值及灌注ADC值,分析不同b值时,各测量参数在良恶性肿瘤之间的差异。结果肝癌、肝脏转移瘤患者病变区的ADC值分别为(1.04±0.36)×10-3mm2/s、(1.46±0.49)×10-3mm2/s;肝囊肿、肝脏血管瘤患者病变区的ADC值分别为(2.38±0.81)×10-3mm2/s、(1.97±0.63)×10-3mm2/s;b值0s/mm2时,肝脏良恶性肿瘤之间ADC值差异均无统计学意义(P>0.05),肝脏灌注ADC值有统计学意义(P<0.05);当b值1000s/mm2时,肝脏良性病变与恶性病变区域内的ADC值差异有统计学意义(P<0.05),肝脏灌注ADC值差异有统计学意义(P<0.05);对于不同的测量感兴趣区位置,在病灶边缘与中心之间,恶性肿瘤的灌注ADC值差异有统计学意义(P<0.05);但是良性肿瘤差异无统计学意义(P>0.05)。结论磁共振弥散成像对肝脏肿瘤的诊断具有很大的价值,特别是高b值及灌注ADC值对肝脏良恶性的鉴别诊断更加准确。
Objective To explore the use of different b values and measurement position of the apparent diffusion coefficient （ADC） value and ADC value of liver peusion in differential diagnosis of benign and malignant tumors of the value. Methods In 120 patients with liver tumors underwent conventional MRI scan and diffusion weighted imaging scans, including 48 cases of Ever tumors and multiple phase enhanced scan. The apparent diffusion coefficient （b） were 0s/mm2 and 1000s/mm2, the lesions measured overall, edge and the center of the surface diffusion coefficient （ADC） value and perfusion ADC value, analysis of different b value, the measured parameters in benign and malignant tumors of the difference between. Results Liver cancer, liver metastases in patients with lesions of the ADC value （1.04 ± 0.36） x 10 -3mm2/s, （1.46 ± 0.49） 10-3mm2/s Ever cysts, liver hemangiomas in patients with lesions of the ADC value （2.38 ± 0.81） x 10-3mm2/s, （1.97 ± 0.63） x 10-3mm2/s, b value of 0s/ram2, the ADC values between benign and malignant liver showed no statistical significance （P〉0.05）, ADC values of Ever perfusion was statistically significant （P〈0.05）, when the b value of 1000s/ram2, the benign and malignant liver lesions in the ADC value was significantly （P〈0.05）, ADC values of Ever perfusion was significantly （P〈0.05） regions of interest for different measurement locations, and the center edge of the lesionbetween the ADC values of tumor perfusion was significantly （P〈0.05） but no significant difference between benign tumors （P〉0.05）. Conclusion Magnetic resonance diffusion imaging in the diagnosis of liver tumors of great value, especially in high b-value ADC values and perfusion of the differential diagnosis of benign and malignant liver is more accurate.
出处
《罕少疾病杂志》
2012年第5期21-25,共5页
Journal of Rare and Uncommon Diseases
关键词
磁共振成像
弥散加权成像
表观扩散系数
肝脏肿瘤
鉴别诊断
Magnetic resonance imaging diffusion-weighted imaging apparent diffusion coefficient livertumors differential diagnosis
