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Apelin/APJ系统在心血管系统中的作用

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摘要 阐述了Apelin/APJ的心血管效应及其与心血管疾病的关系。Apelin是G蛋白偶联受体APJ的内源性配体,在心血管系统高度表达,是一种重要的生理调节肽。Apelin/APJ系统具有正性肌力、扩张血管、降血压、促进血管生成、抑制心肌细胞肥大等重要的心血管保护作用,对治疗心力衰竭、高血压、缺血/缺氧性心血管疾病、心肌缺血-再灌注损伤等疾病有重要意义。
作者 梁莹 吴星恒
出处 《南昌大学学报(医学版)》 CAS 2012年第8期92-95,共4页 Journal of Nanchang University:Medical Sciences
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参考文献32

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