摘要
目的比较术前和术后不同时间角膜不规则状态的变化,评价个体化准分子激光上皮下角膜磨镶术(laser-assisted subepithelial keratomileusis,LASEK)治疗不规则散光的效果。方法收集曾行眼前节全景仪引导的个体化LASEK手术治疗的不规则散光患者23例(40眼)的临床资料。所有患者在术前和术后1个月、3个月和6个月均行眼前节全景仪检查。并对手术前后所有患者的裸眼视力(uncorrected visual acuity,UCVA)、最佳矫正视力(best corrected visual acuity,BCVA)、角膜表面非球面性(Q值)、角膜表面变异指数(index of surface variance,ISV)等进行分析比较。结果 UCVA术前为0.39±0.15,术后6个月为0.95±0.11。BCVA术前为0.79±0.20,术后6个月为1.00±0.04。UCVA、BCVA和术前相比差异有统计学意义(P<0.05)。Q值术前为+0.66±0.28,术后1、3、6个月时分别为+0.24±0.58、+0.41±0.49、+0.38±0.53,术前与术后比较差异有统计学意义(P<0.05);ISV术前为55±10,术后6个月降低为35±8,差异具有统计学意义(P<0.05)。结论眼前节全景仪引导的个体化LASEK手术能显著提高患者的UCVA,整体上改善角膜不规则状态。
Objective To evaluate the clinical effect of oculyzer - guided laser - assisted of 23 cases （40 eyes） underwent oculyzerguided LASEK for irregular astigmatism were collected. All patients were detected by oculyzer before operation and at 1 month, 3 months, and 6 months after operation, respectively. Uncorrected visual acuity （UCVA）, best spectacle corrected visual acuity （BSCVA） ,Q value,index of surface variance （ISV） were analyzed and compared between before and after operation. Results UCVA changed significantly from 0.39 ± 0.15 before operation to 0.95 ± 0.11 at 6 months after operation. BCVA changed significantly from 0.79 ± 0.20 before operation to 1.00 ± 0. 04 at 6 months after operation. UCVA and BCVA at preoperative and different postoperative time points were statistically different （ P 〈 0. 05 ）. Q value changed significantly from ＋ 0.66 ± 0.28 before operation to ＋ 0. 24 ± 0.58, ＋ 0.41 ± 0.49 and ＋ 0.38 ± 0.53 at 1,3 and 6 months after operation, respectively （P 〈 0. 05 ）. There were significant differences in Q value between before and after operation （ P 〈 0. 05 ）. ISV changed significantly from 55 ± 10 before operation to 35 ± 8 at 6 months after operation, and there was statistically significant difference （ P 〈 0.05 ）. Conclusion Oculyzer - guided LASEK shows significant increase of UCVA and BCVA, and improvement of regular status of cornea.
出处
《河北医科大学学报》
CAS
2012年第10期1144-1147,共4页
Journal of Hebei Medical University
基金
河北省卫生厅科研基金项目(20110570)
关键词
散光
角膜磨镶术
激光原位
治疗结果
astigmatism
keratomileusis, laser in situ
treatment outcome
