摘要
目的探讨多灶性运动神经病(multifocal motor neuropathy,MMN)临床表现及电生理特点。方法回顾性分析11例MMN患者的临床表现及电生理结果。结果 11例患者中,男8例,女3例,均为缓慢进展的非对称起病,远端重于近端,伴有肌肉萎缩9例,主观感觉障碍2例,腱反射减弱10例。电生理检查示:正中神经、尺神经等运动神经的持续性多灶性传导阻滞是MMN患者的特征性改变。结论神经电生理检查有助于MMN的早期诊断,利于疾病的早期治疗及预后。
Objective To analyze clinical and electrophysiological characteristics of multifocal motor neuropathy（MMN）.Methods The results including clinical manifestations and electrophysiological changes of 11 patients with MMN were retrospectively analyzed.Results There were 8 males and 3 females in the study.They had in common slow progress,and asymmetric onset.In addition,and it was severer in the remote muscles than in the proximal muscles.The investigation also showed muscle atrophy in 9 cases,the subjective sensory disturbances in 2 cases,reduced tendon reflexes in 10 cases.The most important finding was the electrophysiological examination changes.The middle nerve and ulnar nerve motor nerve of multifocal persistent conduction block was characterized by neurophysiologic changes in patients with MMN.Conclusion Neurophysiologic examination in MNN is helpful in early diagnosis and early treatment with better prognosis.
出处
《白求恩军医学院学报》
2012年第4期268-269,共2页
Journal of Bethune Military Medical College
关键词
多灶性运动神经病
电生理
传导阻滞
Multifocal motor neuropathy
Electrophysiology
Conduction block
