摘要
目的探讨ABCD。评分法结合三种影像学方法对短暂性脑缺血发作(TIA)患者脑梗死的发生进行风险评估。方法选择2007年1月至2011年12月就诊于我院的578例TIA患者,采用ABCD。评分法、磁共振弥散加权成像(DWI)、磁共振血管造影(MRA)及颈动脉彩色多普勒超声(CDFI)对TIA后发生脑梗死的危险度进行分组评估,随访2、7、30d内脑梗死发生率。结果578例TIA患者2、7、30d内发生脑梗死者分别为37例(6.40%)、47例(8.13%)、61例(10.55%);单用ABCD。评分法对]rIA后发生脑梗死危险分层研究发现,高危组(35例)2、7、30d内发生脑梗死者分别为15例(42.86%)、18例(51.43%)、21例(60.00%);ABCD。〉3分且DWI阳性者(51例)TIA后2、7、30d发生脑梗死者达28例(54.90%)、31例(60.78%)、38例(74.51%);ABCD。〉3分且MRA脑动脉狭窄者(36例)TlA后2、7、30d发生脑梗死者达22例(61.11%)、24例(66.67%)、30例(83.33%),ABCD。〉3分且CDFI颈动脉粥样斑块致管腔狭窄者(35例)其结果为21例(60.00%)、23例(65.71%)、28例(80.00%);三种方式对高危TIA患者短期发生脑梗死的评估价值比较差异无统计学意义(P均〉0.05)。结论TIA患者在短期内可进展为脑梗死;ABCD。评分法对TIA后2~30d内脑梗死发生有一定的预测价值,但仅为临床简单评估方法;对ABCD。评分〉3分的中、高危患者可结合DWI、MRA等检查进一步提高预测的准确性,帮助临床医师更好地识别脑梗死发生的高危患者。
Objective To investigate the risk of cerebral infarction on patients with transient ischemic attack (TIA) by combining ABCD2 score and three imaging methods. Methods Five hundred and seventy-eight patients with TIA visiting our hospital from January 2007 to December 2011 were assessed for the risk of cerebral infarction after TIA by ABCD2 score method, magnetic resonance diffusion weighted imaging (DWI) , magnetic resonance angiography (MRA) and carotid artery color Doppler imaging (CDFI). Cases were followed up on 2 d,7 d and 30 d for incidence of cerebral infarction. Results Cerebral infarction occurred in 37 cases (6. 40% ) ,47 cases (8.13%) and 61 cases ( 10. 55% ) on day 2 ,day 7 and day 30. The occurrence of cerebral infarction after TIA in high risk group (35 cases ) by single ABCD2 score was found in 15 eases (42. 86% ) ,18 cases (51.43%) and 21 cases (60. 00% ) on day 2,day 7 and day 30. Twenty-eight cases (54. 90% ) ,31 eases (60. 78% ), and 38 cases (74. 51% ) of patients after TIA with ABCD2 〉 3 and DWI positivity (51 cases) suffered cerebral infarction on day 2, day 7 and day 30. Cerebral infarction occurred in 22 cases (61.11% ), 24 cases (66. 67% ) and 30 cases ( 83.33% ) of patients with ABCD2 〉 3 points and cerebral artery stenosis (36 cases) on day 2,day 7 and day 30 after TIA. The occurrence of cerebral infarction after TIA on day 2, day 7 and day 30 were in 21 cases (60. 00% ) ,23 cases (65.71%) ,28 cases (80.00%) of the patients with ABCD2 〉 3 points and the carotid artery atheroma-caused bureaucratic stenosis (35 cases). There were no significant difference in the value of three methods to assess the risk of cerebral infarction in high-risk TIA groups (P 〉 0. 05). Conclusion TIA patients can progress to cerebral infarction in the short term. There are some predictive value by ABCD2 score from 2 to 30 days for cerebral infarction occurring after TIA, but it is only a simple clinical assessm
出处
《中国综合临床》
2012年第11期1168-1172,共5页
Clinical Medicine of China