摘要
婴幼儿血管瘤(IH)是婴幼儿常见的良性肿瘤之一,60%发生于头颈部。IH具有自限性,但是仍有10%的婴幼儿需要治疗。目前临床上常用的治疗方法包括激素治疗、干扰素治疗、硬化治疗、激光治疗等,但均存在一定不足或不良反应。近来,普萘洛尔被证明对增生期血管瘤具有明显的消退作用。本文就普萘洛尔治疗血管瘤的分子机制、临床应用、不良反应等相关问题进行简要综述。
Infantile haemangioma is a kind of the commonest childhood tumours and frequently occured in the head and neck region. They have a self-limiting course, but approximately 10% lesions require various treatment. Current clinical treatment include systemic or intralesional corticosteroids, vincristine, alpha-interferon, sclerotherapy, laser, or comprehensive of these therapies. Recent reports have highlighted the impressive efficacy of propranolol in treating rapidly proliferating haemangioma. This review focuses on the molecule mechanism of propranolol to treatment of haemangioma, clinical application and adverse respones.
出处
《国际口腔医学杂志》
CAS
2012年第6期814-817,共4页
International Journal of Stomatology
基金
广东省自然科学基金资助项目(10151008901000025)
广东省科技计划基金资助项目(2009B050700024
2009B060700096)
关键词
普萘洛尔
婴幼儿血管瘤
头颈部
propranolol
infantile haemangioma
head and neck
