期刊文献+

12例胃肠道外间质瘤的诊治报告 被引量:6

下载PDF
导出
摘要 目的探讨胃肠道外间质瘤(extragastrointestinal stromal tumor,EGIST)的临床特征、诊断、鉴别诊断及治疗。方法回顾性分析1999年9月至2011年9月收治的12例EGIST的临床病理资料。结果 EGIST临床表现无特异性,除2例肿瘤复发再次手术者有明确诊断外,其余术前均未确诊。全组均经手术治疗,肿瘤位于小肠系膜5例、大网膜4例、腹膜后2例、卵巢1例,平均直径为12.8cm。9例完整切除,2例姑息切除,1例仅行活检术,其中联合脏器切除3例。免疫组化CD117、CD34及α-SMA阳性率分别为100%、58.3%及33.3%,随访12~126个月,4例死于肿瘤复发转移,3例带瘤生存,其余5例未见复发。复发3例予甲磺酸伊马替尼治疗后部分缓解。结论 EGIST临床少见,缺乏特异性临床表现,术前确诊率低。外科手术是唯一能治愈的方法,甲磺酸伊马替尼可能有预防复发的作用。
出处 《中国肿瘤外科杂志》 CAS 2012年第5期296-297,共2页 Chinese Journal of Surgical Oncology
  • 相关文献

参考文献7

  • 1毕建威,张浩,申晓军.胃肠外间质瘤的诊断与治疗[J].中国实用外科杂志,2010,30(4):312-314. 被引量:16
  • 2Emory TS, Sobin LH, Lukes L, et al. Prognosis of gastrointestinal smooth-muscle (stromal) tumors: dependence on anatomicsite[J]. AmJSurgPathol, 1999, 23(1):82-87. 被引量:1
  • 3Kim HC, l,ee JM, Kim SH, et al. Primary gastrointestinal stromal tumors in the omentum angmesentery: CT findings and pathologic ton'elations [ J ]. AJR, 2006, 182 ( 6 ) : 1463-1467. 被引量:1
  • 4Mollna I, Scamon LG, Cope/and L J, et al. Reclassification of leiomyosarcoma as an extra-gastrointestinal stromal tumor of the gy- necologic tract [ J ].. Int J Gynecol Pathol, 2009, 28 : 458463. 被引量:1
  • 5Clary BM, DeMatteo RP, Lewis JJ, et al. Gastrointestinal stromal tumors and leiomyosarcoma of" the abdomen and retroperitoneum: a clinical comparison[J]. Ann Surg OncoI, 2001, 8(4) :290. 被引量:1
  • 6詹文华,王鹏志,邵永孚,伍晓汀,顾晋,李荣,万德森,丁克峰,师英强,于吉人,卢辉山,邹小明,毕建威,孙益红,陆云飞,陈道达,张信华.伊马替尼术后辅助治疗胃肠间质瘤的多中心前瞻性临床试验中期报告[J].中华胃肠外科杂志,2006,9(5):383-387. 被引量:85
  • 7Agaimy A, Wunsch PH. Gastrointestinal stroma] tumours:aregular origin in the muscularis propria, but an extremely diverse gross presentation : A review of 200 eases to cridcall'j re-evaluate the con- cept of so-called extra-gastrointestinal stromal tumours[ J ]. Lange- nbeeks Arch Surg, 2006, 391 (4) :322-329. 被引量:1

二级参考文献24

  • 1毕建威,经纬,魏国,苏明,唐晓军.胃肠道间质瘤46例临床诊治分析[J].中国实用外科杂志,2005,25(11):684-685. 被引量:20
  • 2郑民华,马君俊.腹腔镜手术治疗胃肠道间质瘤[J].中国实用外科杂志,2006,26(8):586-588. 被引量:26
  • 3Mudan SS,Conlon KC,Woodruff J,et al.Salvage surgery in recurrent gastrointestinal sarcoma:prognostic factors to guide patient selection.Cancer,2000,88:66-74. 被引量:1
  • 4DeMatteo RP,Lewis JJ,Leung D,et al.Two hundred gastrointestinal stromal tumors:recurrence patterns and prognostic factors for survival.Ann Surg,2000,231:51-58. 被引量:1
  • 5Mocellin S,Mencarelli R,Foletto M,et al.Gastrointestinal stromal tumors:from a surgical to a molecular approach.Int J Cancer,2003,107:171-176. 被引量:1
  • 6Dematteo RP,Shah A,Fong Y,et al.Results of hepatic resection for sarcoma metastatic to liver.Ann Surg,2001,234:540-548. 被引量:1
  • 7Husted TL,Neff G,Thomas MJ,et al.Liver transplantation for primary or metastatic sarcoma to the liver.Am J Transplant,2006,6:392-397. 被引量:1
  • 8Blanke CD,Demetri GD,Von Mehren M,et al.kong-term follow-up of a phase Ⅱ randomized trial in advanced gastrointestinal stromal tumor (GIST) patients treated with imatinib mesylate.Abstract No:9528,J Clin Oncol,2006 ASCO Annual Meeting Proceedings Part Ⅰ.Vol 24,No.18S. 被引量:1
  • 9Perez EA,Livingstone AS,Franceschi D,et al.Current incidence and outcomes of gastrointestinal mesenchymal tumors including gastrointestinal stromal tumors.J Am Coll Surg,2006,202:623-629. 被引量:1
  • 10Goettsch WG,Bos SD,Broekveldt-Postma N,et al.Incidence of gastrointestinal stromal tumours is underestimated:results of a nation-wide study.Eur J Cancer,2005,41:2868-2872. 被引量:1

共引文献97

同被引文献79

引证文献6

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部