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新疆维吾尔族与汉族前列腺癌患者年龄及病理构成分析

Onset age and pathology of prostate cancer in Uygurs and Hans in Xinjiang
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摘要 目的:对新疆维、汉两个民族前列腺癌患者的年龄及病理构成情况进行比较分析。方法:收集2002年1月至2011年12月确诊为前列腺癌患者518例,维吾尔族138例,汉族380例,按照不同年份、不同年龄段及不同Gleason评分进行分组并对其构成比进行分析。结果:新疆维、汉两民族前列腺癌的发病率均呈逐年递增的趋势,两民族年份构成比之间无统计学差异(χ2=1.063,P=0.900);维、汉两族前列腺癌患者的年龄中位数及众数分别为:70岁,63岁;73岁,71岁;两民族的高发年龄均为70~79岁,维吾尔族前列腺癌患者50~59岁及60~69岁年龄组构成比高于汉族患者,80~89岁组低于汉族,差异有统计学意义(χ2=40.375,P<0.01);维、汉两族前列腺癌Gleason评分的中位数及众数分别为7分,6分;8分,8分;两个民族Gleason评分构成比之间无统计学差异(χ2=0.991,P<0.01)。结论:维吾尔族前列腺癌患者年龄构成比不同于汉族,两民族前列腺癌患者在年度增长及病理分期的构成比方面有一定的相似性。 Objective: To investigate the differences in the onset age and pathology of prostate cancer between Uygurs and Hans in Xinjiang.Methods: We enrolled in this study 518 patients(138 Uygurs and 380 Hans) with prostate cancer confirmed between January 2002 and December 2011.We conducted comparative analyses on their ages,years of diagnosis and Gleason scores.Results: The incidence of prostate cancer increased year by year in both Uygur and Han people,but no statistically significant differences were found in the years of diagnosis between the two groups(χ2 = 1.063,P = 0.900).The median and mode ages of the Uygur patients were 70 and 63 years,and those of the Hans 73 and 71 years.The predilection age of prostate cancer was 70-79 years in both the two groups.The Uygurs showed a significantly higher incidence of prostate cancer in the 50-59 yr and 60-69 yr groups than the Hans,but the results were just the opposite in the 80-89 yr group(χ2 = 40.375,P = 0.01).The median and mode of Gleason scores were 7 and 6 in the Uygurs,and 8 and 8 in the Hans,respectively,with no significant difference between the two groups(χ2 = 0.991,P = 0.01).Conclusion: The Uygurs differed from the Hans in the age of prostate cancer onset,but there were no significant differences in the annually increased incidence and pathological stage of prostate cancer between the Uygurs and Hans in Xinjiang.
出处 《中华男科学杂志》 CAS CSCD 2012年第10期900-903,共4页 National Journal of Andrology
关键词 前列腺癌 民族 维吾尔族 汉族 流行病学 prostate cancer ethnic group Uygur Han epidemiology
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