摘要
目的评估胃癌手术方式对手术创伤程度的影响。方法1994年8月至2011if-4月,中山大学胃肠胰外科施行病灶切除术的1499例胃癌患者,依手术方式分为根治性切除组(根治组,1344例),姑息性切除组(姑息组,155例),并根据胃切除方式、根治程度、联合脏器切除进一步划分亚组,以手术时间、术后住院日、术中输血量、并发症发生率作为手术创伤程度评估指标,比较各组、各亚组的手术创伤程度。结果根治组和姑息组的中位输血量(Q1,Q3)分别为0(0,600)比400(0,800)ml(P〈0.05);两组的手术时间、术后住院日、并发症差异均无统计学意义(均P〉0.05)。对远端胃切除病例,根治组和姑息组的中位输血量(Q1,Q3)分别为0(0,400)比400(200,800)ml(P〈0.05);两组的手术时间、术后住院日、并发症差异均无统计学意义(均P〉0.05)。对全胃切除病例,根治组、姑息组的手术时间、中位输血量、术后住院日、并发症差异均无统计学意义(均P〉0.05)。在根治组病例中,接受D1、D2、D3、腹主动脉旁淋巴结清扫(PAND)患者的手术时间,术后住院日,中位输血量(Q1,Q3)差异均有统计学意义[(248±71)、(271±72)、(309±96)、(351±103)min,(13±4)、(16±12)、(18±11)、(20±19)d,0(0,500),0(0,600),400(0,800),600(200,1000)ml,均P〈0.05],而并发症差异无统计学意义(P〉0.05)。在根治组病例中,无、有联合脏器切除患者的手术时间、术后住院日、中位输血量分别为(264±66)比(315±96)min,(15±11)比(19±15)d,0(0,400)比400(0,800)ml,差异均有统计学意义(均P〈0.05),而并发症差异无统计学意义(P〉0.05)。结论较姑息性切除手术相比,根治性手术并不增加胃癌患者的手术创伤。对接受根治术�
Objective To evaluate the impact of surgical modality for gastric cancer on operational trauma. Methods A total of 1499 cases of gastric cancer undergoing surgical procedures were divided into the groups of radical resection (RR, n = 1344) and palliative resection group( NRR,n = 155 ) according to their surgical modalities. And they were further divided into sub-groups according to the profiles of gastrectomy, extent of lymphadenectomy and multiorganic resection. The extent of operational trauma ( as evaluated by operative duration, transfusion volume, postoperative hospital day and incidence of complications) was compared in different groups and subgroups. Results In RR and NRR groups, median transfusion volume ( Q1, Q3 ) was 0 (0, 600) vs 400 (0, 800) ml respectively. There was significant difference ( P 〈 0. 05 ). No significant difference existed in operative duration, postoperative hospital day or incidence of complications between two groups ( all P 〉 0. 05 ). In cases of distal gastrectomy, median transfusion volume was 0 ( 0, 400 ) vs 400 ( 200, 800) ml in RR and NRR groups ( P 〈 0. 05 ). No significant difference existed in operative duration, postoperative hospital day or incidence of complications between two groups ( all P 〉 0.05 ). In cases of total gastrectomy, no significant difference existed in operative duration, postoperative hospital day, median transfusion volume or incidence of complications between two groups ( all P 〉 0. 05). In RR group, for the cases treated by D1, D2, D3 and paraaortic lymph node dissection (PAND), there were significant differences in operative duration( (248 ±71 ), (271 ±72),(309±96) , (351 ± 103) min), postoperative hospital day( ( 13 ±4), ( 16 ± 12) , ( 18 ±11 ) , (20 ± 19) days), median transfusion volume(0(0, 500), 0(0, 600), 400(0, 800) , 600(200, 1000) ml) ( all P 〈 0. 05 ). But no significant difference existed in incidence
出处
《中华医学杂志》
CAS
CSCD
北大核心
2012年第38期2694-2698,共5页
National Medical Journal of China
关键词
胃肿瘤
创伤和损伤
手术方式
Stomach neoplasms
Wounds and injuries
Surgical procedures