摘要
目的探讨多层螺旋CT在乳腺癌新辅助化疗疗效评价中的应用价值,以求进一步明确螺旋CT对乳腺癌新辅助化疗疗效的预测评估。方法 25例初治原发性乳腺癌患者,均为女性,年龄33～62岁,平均年龄48.9岁,全组病例化疗前行粗针穿刺明确诊断,分别行2～4周期新辅助化疗,新辅助化疗前后行螺旋CT扫描,测量化疗前后肿块数目及大小、淋巴结数目及大小、肿块强化模式等。结果多层螺旋CT检查评价乳腺癌病灶变化与病理学评价的符合率90.9%。结论多层螺旋CT结合三维重建技术能够准确反映出乳腺癌病灶及淋巴结化疗前后的信息,并能准确的反映乳腺癌病灶化疗前后的血流信息,对预测乳腺癌新辅助化疗疗效具有一定的应用价值。
Objective To investigate the value of CT of breast cancer in evaluation of therapeutic effect of neoadjuvant chemotherapy. Methods 25 patients with primary breast cancers were women, ranging from 33 to 62 years of age, with a mean age of 48.9 years. All patients underwent the core needle biopsy and confirmed diagnosis before neoadjuvant therapy. Treatment course was 2-4 periods. CT was examined before and after neoadjuvant therapy. The tumor number and size, lymph node number and size, enhancement mode were measured before and after neoadjuvant therapy. Results According to the length of breast mass lesion, the accuracy for CT in evaluating effect of neoadjuvant chemotherapy was 90.9%. Conclusion CT combined with 3D reconstruction technique can reflect the mass and lymph node information before and after neoadjuvant therapy, and can also reflect the blood flow information of the mass. It was useful to forecast the effect of neoadjuvant chemotherapy of breast cancer.
出处
《医学影像学杂志》
2012年第10期1677-1680,共4页
Journal of Medical Imaging
基金
浙江省医药卫生科学研究基金项目计划(2004B209)
丽水市科技局科技计划项目(2010JYZB23)
关键词
乳腺肿瘤
新辅助化疗
体层摄影术
X线计算机
Breast cancer
Neoadjuvant chemotherapy
CT
Tomography, X-ray computed
