期刊文献+

围术期应用黏液促排剂治疗中耳炎性疾病的临床研究 被引量:3

Clinical research on the perioperative application of eucalyptol-limonene-pinene enteric-coated capsules in patients with middle ear inflammatory diseases
下载PDF
导出
摘要 目的探讨围术期应用黏液促排剂对中耳炎性疾病术后恢复的影响。方法将136例(144耳)诊断为分泌性中耳炎35例(40耳)、慢性化脓性中耳炎49例(52耳)、胆脂瘤型中耳炎52例(52耳)的患者随机分为治疗组和对照组。两组患者实施相同手术治疗。对照组仅手术治疗,治疗组手术当天服用桉柠蒎肠溶胶囊,0.3g,2次/d,连续服用7~8周。两组患者于术后第2、4、6、8周进行听力学检查及评估,观察两组疗效。结果分泌性中耳炎、慢性化脓性中耳炎、胆脂瘤型中耳炎治疗组术后第4周及第6周纯音测听检查、患者主观症状恢复优于对照组,差异有统计学意义(P<0.05);分泌性中耳炎治疗组术后第4周及第6周咽鼓管功能恢复较对照组有统计学意义(P<0.05);慢性化脓性中耳炎治疗组第8周咽鼓管功能恢复较对照组有统计学意义(P<0.05)。结论中耳炎性疾病以手术治疗为主,并能取得满意疗效。围术期服用黏液促排剂,可改善咽鼓管功能,缩短术腔恢复时间,提高手术疗效,改善患者生活质量。 Objective to investigate the therapeutic effects of perioperative application of eucalyptol-limonene-pinene enteric-coated capsules in the patients secretory otitis media,cholestoma and chronic otitis media.Methods 35 patients diagnosed as secretary otitis media,49 patients diagnose as chronic suppurative otitis media and 52 patients diagnosed as cholestoma otitis media were enrolled in this study.The patients were divided into the treatment group and the control group:the patients in the control group received corresponding surgery and the patients in the treatment group were perioperative applied with the eucalyptol-limonene-pinene enteric-coated capsules.On the time point of 2nd week,4th week,6th week and 8th week afer surger,the theraputic effect was observed by analysis of the symptoms,audiological examination and eustachian tube function assessment.Results The result of subjective sympom and audiological examination showed dramatical improvement in all the patients on the time point of 4th week and 6th week after surgery compared with the control group.The eustachian tube funcion of the patients with secretory otitis media in the treatment group was better than the one in the control group on the time point of 4th week and 6th week,and the eustachian tube funcion of the patients with the chronic suppurative otitis media in the treatment group showed dramatical improvements on the time point of 8 week (P〈0.05).Conclusion The perioperative application of eucalyptol-limonene-pinene enteric-coated capsules could improve theraputic effects and shorten the recovery period.
出处 《中国实用医药》 2012年第27期16-19,共4页 China Practical Medicine
关键词 中耳炎性疾病 咽鼓管功能 桉柠蒎肠溶胶囊 secretory otitis media Eustachian tube function Eucalyptol-limonene-pinene enteric-coated capsules
  • 相关文献

参考文献25

  • 1Tomomi Yamamoto-Fukuda,Haruo Takahashi,and Takehiko Koji,Animal Models of Middle Ear Cholesteatoma,Journal of Biomedicine and Biotechnology.2011. 被引量:1
  • 2甄宏韬,王春芳,崔永华,高起学,葛新.正常人咽鼓管功能的综合法检测[J].临床耳鼻咽喉科杂志,2000,14(4):160-161. 被引量:21
  • 3肖社平,谭代忠,廖敏清,杨鹿龄,涂雪峰.声导抗测试对慢性化脓性中耳炎咽鼓管功能的评价[J].临床耳鼻咽喉科杂志,2006,20(7):306-308. 被引量:7
  • 4黄选兆,汪吉宝.实用耳鼻咽喉科学.第2版.北京:人民卫生出版社,2010:837-860. 被引量:3
  • 5H Sudhoff,M Tos,Pathogenesis of attic cholesteatoma:clinicla and immunohistochemical support for combination of retraction theory and proliferation theory,American Journal,2000,21(6):768-792. 被引量:1
  • 6H Sudhoff,M.Tos.Pathogenesis of attic cholesteatoma:European Archives of Oto-Rhino-Laryngology,2007,264(10):1137-1143. 被引量:1
  • 7Sehhati-ChafaiI-Leuwer S,Wenzel S,Bschorer R,et al.Pathophysiology of the Eustachian tube-relevant new aspects for the head and neck surgeon.Journal of Cranio-Maxillofacial Surgery,2006,34:351-354. 被引量:1
  • 8FLISBERG K,INGELSTEDT S,ORTEGREN U.The valve and "locking" mechanisms of the eustachian tube.Acta Otolaryngol Suppl,1963,182:57-68. 被引量:1
  • 9Masashi M,Sakakura Y,Shimizu Y,et al.Ultrastructure of mucous blanket in otitis media with effusion.Ann Otol Rhinol Laryng ol,1988,97:313. 被引量:1
  • 10Borkowski G,Gurr A,Stark T,et al.Functional and morphological defects of the mucociliary system in secretory otitis media.Laryngorhinootologie,2000,79(3):135-138. 被引量:1

二级参考文献21

  • 1杨宝柱,江炜,王靖岱,阳永荣.气相流化床聚乙烯颗粒粒径分布模型的研究[J].高校化学工程学报,2005,19(4):461-467. 被引量:19
  • 2高立.祛痰宁对呼吸道疾病386例的疗效[J].新药与临床,1989,8(6):343-346. 被引量:2
  • 3梁勇,罗志强.声导抗测试与咽鼓管开放类型的判别[J].中国耳鼻咽喉颅底外科杂志,1996,2(1):9-11. 被引量:1
  • 4Matzke H. Experienceswith Gelomyrtol in the treatment of bronchitis[J].MunchMedWochenschr, 1961, 29 (103) : 1881- 1882. 被引量:1
  • 5Kurz JF. Secretolysis through gelomyrtol [J].ZAllgemeinmed, 1970, 46 (32): 1623-1627. 被引量:1
  • 6Matthys H, de Mey C, Carls C, et al, Efficacy and tolerability ofmyrtol standardized in acute bronchitis [J]. Arzneimittelforschung, 2000, 50 (8):700-711. 被引量:1
  • 7UlmerWT, SchottD. Chronic obstructive bronchitis. Effect of Gelomyrtol forte in a p lacebocontrolled double2blind study [J].Fortschr Med, 1991, 109 (27): 547-550. 被引量:1
  • 8Sengespeik HC, Zimmermann T, Peike C, et al. Myrtol standardized in the treatment of acute and chronic respiratory infections in children [J]. Arzneimittelforschung, 1998, 48 (10) : 990-994. 被引量:1
  • 9Meister R, Wittig T, BeuscherN, et al. Efficacy and tolerability ofmyrtol standardized in longterm treatment of chronic bronchitis. A double blind, placebocontrolled study. Study Group Investigators[J]. Arzneimittelforschung, 1999, 49 ( 4 ): 351-358. 被引量:1
  • 10Beuscher N, Kietzmann M, Bien E, et al. Interference of Myrtol Standardized with Inflammatory and Allergic Mediators [J].Arzneimittelforsehung, 1998, 48 (10): 985-989. 被引量:1

共引文献75

同被引文献38

引证文献3

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部