摘要
目的:了解妊娠期糖尿病(GDM)孕妇血清chemerin水平的变化及其临床意义。方法:采用酶联免疫吸附法测定38例GDM患者(GDM组)及40例糖耐量正常孕妇(对照组)血清chemerin水平,同时测定受试者空腹血糖(FPG),三酰甘油(TG),总胆固醇(TC),高密度脂蛋白胆固醇(HDL-C),空腹胰岛素(FINS),计算胰岛素抵抗指数(HOMA-IR)。结果:(1)GDM组血清chemerin水平显著高于对照组(P<0.05)。(2)GDM组FPG、TG、FINS、HOMA-IR水平均显著高于对照组(P均<0.05)。GDM组TC,HDL-C水平与对照组的差异无统计学意义。(3)GDM组血清chemerin水平与TG呈显著正相关(r=0.726,P<0.05)。结论:GDM患者血清chemerin水平升高,可能参与了妊娠期糖尿病孕妇糖代谢紊乱。
Objective：To study the relationship between chemerin and GDM.Methods：The serum chemerin levels in pregnant women with GDM（38 cases）and in normal pregnant women（40 cases）were determined individually by Enzyme-linked immunosorbent assay（ELISA）.Fasting plasma glucose（FPG）,blood glycerin three greases（TG）,fasting Insulin levels（FINS）,insulin resistance index（HOMA-IR） were also tested.Results：（1） The serum level of chemerin was significantly higher in GDM group than that in control group（P0.05）.（2）The serum levels of FPG,FINS,TG,HOMA-IR were significantly higher in GDM group than that in control group（P0.05）.The serum levels of TG、HDL-C were not significantly different between the two groups.（3）There were significant correlations between the levels of serum chemerin and TG（r=0.726,P0.05）.Conclusions：The levels of serum chemerin in pregnant women with GDM obviously increase,and the levels of serum chemerin may play a role in pregnant women with GDM.
出处
《现代妇产科进展》
CSCD
2012年第9期700-701,705,共3页
Progress in Obstetrics and Gynecology
