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TAE治疗大咯血的疗效分析 被引量:10

Analysis of transcatheter arterial embolization for the treatment of life-threatening hemoptysis using Kaplan-Meier curve
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摘要 目的:观察经导管动脉栓塞术(TAE)治疗大咯血的近期及远期疗效,分析影响大咯血远期疗效的因素。方法:回顾性分析本院采用TAE治疗大咯血的52例患者的病例资料,包括栓塞前后血管造影表现、咯血的责任血管、复发咯血时间、并发症。采用Kaplan-Meier方法计算TAE术后咯血的控制率。结果:大咯血的病因包括肺内肿瘤16例、肺结核14例、支气管扩张11例、肺结核合并支气管扩张8例、肺内血管畸形1例、不能明确病因2例。52例患者总共栓塞了72支支气管动脉及13支非支气管动脉,止血成功率90%(47/52)。随访1~57个月,平均29个月,共有14例(30%)复发咯血。复发率最高组为肺结核合并支气管扩张组有4例复发,复发率50%(4/8);肺结核组5例复发,复发率36%(5/14);支气管扩张组2例复发咯血,复发率18%(2/11);复发率最低组为肺内肿瘤组(12.5%,2/16)。Kaplan-Meier方法分析本组患者术后1个月、12个月、48个月咯血控制率分别为85%、70%、68%。结论:血管内栓塞法对大咯血患者是一种安全有效的治疗方法,术后积极治疗原发病及预防控制感染是提高远期疗效的有效手段。 Objective:To review the short-term and long-term results in patients with life-threatening hemoptysis treated by transcatheter arterial embolization(TAE),and to analyze the factors of long-term outcome.Methods:The clinical materials of 52 patients having life-threatening hemoptysis and treated with TAE were analyzed retrospectively,including the angiographic manifestations before and after TAE,the responsible bleeding arteries,time of recurrence and complications.Kaplan-Meier curves were used to analyze the rate of hemotysis controlled.Results:The major causes of hemoptysis included lung tumor(16 cases),tuberculosis(14 cases),bronchiectasis(11 cases),bronchiectasis accompanied with tuberculosis(8 cases),vascular anomaly(1 cases) and unknown cause(2 cases).Totally 72 bronchial arteries and 13 non-bronchial arteries were embolized.The rate of success was 90%(47/52 cases).All patients were followed up over a period ranging from 1 month to 57 months(mean 29 months),and 14 cases had hemoptysis recurrence.The highest recurrent rate was assessed in the group of tuberculosis accompanied with bronchiectasis(4/8 cases,50%).Recurrent hemoptysis in the group of tuberculosis was seen in 5 cases(5/14,36%),in the group of bronchiectasis was 18%(2/11 cases).The lowest recurrent rate was seen in the group of lung tumor(2/16 cases,12.5%).The rate of hemoptysis controlled calculated with Kaplan-Meier curve at 1,12 and 48 months was 85%,70% and 68% respectively.Conclusion:TAE is an effective and safe approach for the treatment of life-threatening hemoptysis.Treating the primary disease and preventing pulmonary infection can effectively improve the therapeutic effect.
出处 《放射学实践》 2012年第10期1124-1127,共4页 Radiologic Practice
关键词 咯血 栓塞 治疗性 治疗结果 Hemoptysis Embolism therapeutic Treatment outcome
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