摘要
本文以原子吸收分光光度法对lO例肝细胞癌及癌周组织进行了Fe、Cu、Zn、Mn的定量测定,并用6例正常肝组织作对照。同时进行了病理形态学研究。结果癌组织Fe、Zn、Mn含量明显低于正常及癌周肝组织(P<0.01),而Cu含量则无差异,血清与癌及癌周组织中Fe、Cu、Zn、含量无相关性。癌组织中微量元素明显降低者多见于透明细胞癌、肝或癌细胞大片坏死及重度脂肪变。
The trace elements including Fe, Zn, Cu and Mn were quantitively analyzed in the tissues of the carcinoma and pericarcinoma from HCC by atomic absorption spectrophotometry. The pathological morphology of the liver was also studied.
Conclusion: Fe, Zn and Mn contents in the carcinoma tissue are lower than in the normal and pericarcinoma tissue. The mean Cu content had no difference among them. There was no correlation between the contents the serum and the tissues. There was significant decrease of Fe, Gu, Zn and Mn contents in clear cell carcinoma, cell necrosis and fatty change; the base membrane formation of sinusoid and decrease in cell organs. which is the cause or effec for HCC, the mechanism of trace element deserves further study.
出处
《军医进修学院学报》
CAS
1990年第2期132-134,共3页
Academic Journal of Pla Postgraduate Medical School
关键词
微量元素
肝细胞瘤
对比研究
Trace elements Flow cytometry Hepatoma Comparative study
