摘要
双胸复合体(BX-C)作为Hox基因簇的两个复合体之一,包括Ultrabithorax(Ubx)、abdominal-A(abd-A)、Abdominal-B(Abd-B)3个基因及其间的顺式调控区域,在动物躯体模式的发育过程中具有重要作用。昆虫双胸复合体基因主要规定其后胸及腹部形态的特异性,通过与其上、下游靶基因一起或以自身基因间的相互调控作用行使功能。本文以模式昆虫果蝇为主,结合家蚕、蝴蝶、赤拟谷盗等,对双胸复合体在昆虫体节规定、附件发育及内部器官分化等过程中的作用与基因间的相互调控关系进行了综述。
As one of the two homeotic gene （Hox） clusters, the bithorax complex （BX-C） contains three genes, namely Ultrabithorax （ Ubx）, abdominaI-A （abd-A） and AbdominaI-B （Abd-B）, and the cis-regulatory regions between them. These genes play important roles in the development of animal body plan. BX-C genes are mainly responsible for deter- mining the identity of posterior thorax and abdominal segments of insect, acting together with their up/downstream genes or through interactive regulation to the expression of themselves. In this article, based on the advances obtained from model insect （fruit fly） and other insects such as silkworm, butterfly and red flour beetle, we reviewed the roles of BX-C in segment determination, appendage development and internal organ differentiation, as well as the regulatory relation- ship between BX-C genes.
出处
《蚕业科学》
CAS
CSCD
北大核心
2012年第5期914-918,共5页
ACTA SERICOLOGICA SINICA
基金
国家自然科学基金项目(No.31072088,30901053)
中央高校基本科研业务费项目(No.XDJK2009C192)
