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用湿度计测定药物溶液的渗透压 被引量:3

Determining osmotic pressure of drug solutions using a humidity meter
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摘要 目的尝试用湿度计测定药物溶液的渗透压。方法以NaCl溶液为模型,采用湿度计测定溶液的渗透压,并与现有的冰点渗透压仪测定值比较。结果湿度计测定渗透压的范围大大超过冰点渗透压仪,两者的测定值基本一致。结论用湿度计测定药物溶液的渗透压的方法简便快捷,还适用于高浓度溶液的测定。 OBJECTIVE To determine osmotic pressure of drug solutions using humidity meter.METHODS The osmotic pressure of NaCl solution was determined with a humidity meter,which was compared with that determined with a freezing point osmometer.RESULTS The osmotic pressure determined with the humidity meter was generally comparable to that determined with the freezing point osmometer,while the determination range of the humidity meter was significantly wider than that of the freezing point osmometer.CONCLUSION Determining osmotic pressure of drug solutions using the humidity meter is simple and rapid,and is able to be used in concentrated solutions.
出处 《华西药学杂志》 CAS CSCD 北大核心 2012年第5期552-554,共3页 West China Journal of Pharmaceutical Sciences
基金 国家自然科学基金资助项目(批准号:30973658)
关键词 渗透压 湿度计 冰点渗透压仪 Osmotic pressure Humidity meter Freezing point osmometer
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参考文献5

  • 1Alessanddro G, Giancarlo C, Franco Maria M, et al. Fast mem- brane osmometer as alternative to freezing point and vapor pres-sure osmometry [ J ]. Anal Chem, 2008,80:2617 - 2622. 被引量:1
  • 2董来鑫,李艳宁,张奎.基于MSC1210的冰点温度测量系统[J].电子测量技术,2008,31(8):151-153. 被引量:5
  • 3Xiancheng Z, Yingli W, Lan C,et al. Detet-mining critical relative humidity by measuring air humidity in equilibrium directly [ J ]. Europ J Pharma Sci ,2010,41:383 - 387. 被引量:1
  • 4李伟琦.冰点下降公式推导的图像解析[J].浙江师范大学学报(自然科学版),2004,27(3):268-271. 被引量:4
  • 5Yingli W, Xiancheng Z, Lin L, et al. Relationship between critical relative humidity and solubility of drugs [ J ]. Drug Dev Ind Pharm ,2011,37 ( 5 ) :547 - 551. 被引量:1

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