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益赛普与甲氨蝶呤治疗关节型银屑病疗效比较 被引量:2

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摘要 目的比较生物制剂益赛普(重组人Ⅱ型肿瘤坏死因子受体一抗体融合蛋白)与甲氨蝶呤治疗关节型银屑病的疗效差异,为临床医师选择合适的药物治疗关节病型银屑病提供参考。方法对48例关节型银屑病患者的病历资料进行回顾分析,其中25例接受益赛普治疗,23例接受甲氨蝶呤治疗。结果治疗2周后,益赛普组和甲氨蝶呤组患者关节疼痛缓解率及皮疹改善率虽有差异,但差异无统计学意义(P〉0.05);治疗6周后,益赛普组患者关节疼痛缓解率及皮疹改善率均显著高于甲氨蝶呤组,差异有统计学意义(P〈0.05)。结论益赛普治疗关节型银屑病的短期疗效与甲氨蝶呤相似,但远期疗效优于甲氨蝶呤。
出处 《中国实用乡村医生杂志》 2012年第19期50-51,共2页 Chinese Practical Journal of Rural Doctor
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