摘要
目的了解有无临床症状的2型糖尿病患者间的胰岛功能和胰岛素抵抗参数的差别。方法选取2型糖尿病患者110例,其中无临床症状的51例,有临床症状的59例,测定BMI(体重指数),血压,Tch(总胆固醇),LDL(低密度脂蛋白),TG(甘油三酯),HbA1c(糖化血红蛋白),空腹血糖,空腹C肽,餐后血糖,餐后C肽等参数,计算胰岛素抵抗指数和胰岛功能指数,同时计算曲线下血糖面积和曲线下C肽面积,进行统计学分析。结果 (1)无症状2型糖尿病患者血糖曲线下面积高于有症状患者,差异有统计学意义(P<0.05);(2)无症状2型糖尿病患者胰岛素抵抗指数高于有症状患者,差异有统计学意义(P<0.05);(3)无症状2型糖尿病患者C肽曲线下面积高于有症状患者,差异有统计学意义(P<0.05)。结论无症状2型糖尿病患者可能较有症状患者有更高的血糖水平和更明显的胰岛素抵抗,临床上应更加关注无症状2型糖尿病患者,早期发现、早期治疗。
Objective To study the comparison of islet function and insulin resistance parameters in 2DM patients with or without clini cal symptoms. Methods We selected 110 cases of 2DM patients,including 51 cases of patients without clinical symptoms, and 59 ca ses of patients with clinical symptoms, determinated their BMI, blood pressure, TCH, LDL, TG, HbA1 c , fasting glucose, functional in dex, and calculated HomaIR, Homaislet, the area under the glucose curve and Cpeptide curve, and did some correlation statistical a nalysis. Results Blood glucose area under the curve, HomaIR and Cpeptide area under the curve in asymptomatic patients with type 2 diabetes were higher than those in sympomatie patients with type 2 diabetes. There were significant differences. Conclusions Maybe there are higher blood sugar levels and insulin resistance in asymptomatie patients with type 2 diabetes than those in symptomatic patients （ with type 2 diabetes）. It is necessary to pay more attention to the asymptomatic type 2 diabetic patients for early detection and early treatment.
出处
《安徽医药》
CAS
2012年第11期1636-1637,共2页
Anhui Medical and Pharmaceutical Journal
关键词
胰岛功能
胰岛素抵抗
临床症状
糖尿病
islet function
insulin resistance
clinical symptoms
diabetes
