摘要
为了观察盐酸戊乙奎醚(PHC)应用于小儿外科手术麻醉前用药效果及不良反应,选取1 535例小儿外科手术,随机分为三组,观察麻醉前用药唾液分泌量、体温和血流动力学变化。结果发现气管插管和拔管时,三组分泌物量有差异(P<0.01)。三组基础体温无差异(P>0.05),组内有差异(P<0.05)。三组基础心率无差异(P>0.05),组内有差异(P<0.01)。三组平均动脉压无差异(P>0.05)。因此PHC 0.04mg/kg应用于小儿外科手术麻醉前用药,能有效抑制唾液腺分泌,维持体温和血流动力学稳定。
To study the influence of PHC as premedication in pediatric surgery, we selected 1 535 cases of pediatric surgeries which were divided into three groups randomly. The results are as follows. There is significant difference of secretion during the endotracheal intubation and extubation（P〈0.01 ）. Temperature comparison： There is significant difference of body temperature among the three groups （P〈0. 05）, while there is no significant difference of basal body temperature （P〉0. 05）. HR： there is significant difference of heart rate among the three groups （P〈0.05）and no significant difference of basal heart rate （P〉0.05）. MAP： there is no significant difference of mean arterial blood pressure （P〉0.05）. Therefore, PHC 0.04mg/kg used in the pediatric surgeries as premedication can effectively inhibit the salivary gland secretion, maintain a stable temperature and hemodynamics.
出处
《医学与哲学（B）》
2012年第9期28-29,41,共3页
Medicine & Philosophy(B)
基金
河南省科学技术厅科技攻关重点项目
项目编号:122102310224
关键词
盐酸戊乙奎醚
麻醉前用药
全身麻醉
penehyclidine hydrochloride（PHC）, premedication, general anesthesia
