摘要
目的:通过扶脾温肾汤治疗8例慢性牙周炎的临床效果,探讨中药治疗慢性牙周炎的临床应用可行性。方法:通过中医辨证论治,筛选出8例符合脾肾阳虚型中重度牙周炎患者,进行中西两法治疗,洁治后给予扶脾温肾中药治疗,用ELISA检测该药治疗前后患者龈沟液中白介素1-β(IL-1β)和白介素-6(IL-6)的含量。结果:治疗后牙周探诊深度(PD)、牙龈出血指数(BI)、牙周附着水平(AL)均有明显下降(P<0.05)。龈沟液中IL-1β及IL-6在服中药1个月后均有明显下降(P<0.05)。结论:中药扶脾温肾汤对脾肾阳虚型慢性牙周炎有明显的改善作用。
To discuss the clinical effect of traditional Chinese medicine,Fupi Wenshen Decoction on periodontitis.Methods： Eight Pishen Yangxu type patients with moderate to severe periodontitis,were treated with Chinese and western methods.After scaling,the patients were treated with a traditional Chinese medicine Fupi Wenshen Decoction.Then the contents of IL-1β and IL-6 in GCF were detected with ELISA.Results： PD,BI and AL dramatically decreased（P0.05）,as well as IL-1β in GCF.After one month treated with the with Chinese medicine,IL-6 also decreased but did not have statistical significance.After one month treated with the Chinese medicine,IL-1βand IL-6 still dramatically decreased compared with the data before treatment（P0.05）.Conclusion： The traditional Chinese medicine Fupi Wenshen Decoction has obvious effects on amelioration of periodontitis.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2012年第10期2699-2702,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
中日友好医院院级课题(No.2010-MS-39)~~
