摘要
目的探讨阿尔茨海默病(AD)、血管性痴呆(VD)的知觉启动效应的变化,了解是否存在内隐记忆与外显记忆的分离现象,讨论其可能的机理及特点。方法 26例AD患者、28例VD患者、24例中老年正常对照均接受简易精神状态检查、临床记忆量表、加工分离程序测验,结果的处理采用单因素方差分析。结果 AD患者意识性提取、自动提取成绩均显著低于中老年正常对照(P均<0.01);VD患者意识性提取成绩均低于中老年对照者(P<0.01),自动提取成绩与中老年对照者比较无统计学差异(P>0.05)。结论 AD、VD的外显记忆损伤,知觉启动效应均保留,研究结果支持多重记忆系统理论。
Objective To evaluate the explicit memory and perceptual implicit memory in patients with Alzheimer＇ s disease（ AD）, vascular dementia（ VD）, in order to study the phenomenon of dissociation between explicit memory and im plicit memory in dementia patients and explore its possible mechanism and characteristics. Methods A total of 26 AD patients, 28 VD patients, and 24 elderly people as normal Controls were estimated by mini-mental state examination, clinical memory scale, and process dissociation procedure （PDP） tasks. Data was analyzed with one-way ANOVA. Results The recollection scores in AD, VD groups decreased significantly when compared with those in elderly control groups in free association tasks （ all P 〈 0.01 ）, whereas the automatic scores had no significant difference among three groups （ all P 〉 0.05）. Conclusions AD, VD patients showed impaired explicit memory, but retained normal semantic and perceptual priming effect. The result of remained implicit memory of dementia patients support the hypothesis of multiple memory systems theory.
出处
《山东医药》
CAS
2012年第33期9-11,共3页
Shandong Medical Journal
基金
山东省科学发展计划项目(2008GG30002058)
关键词
阿尔茨海默病
痴呆
血管性
知觉启动效应
Alzheime disease
dementia, vascular
perceptual priming effect
