摘要
目的了解呼伦贝尔地区真菌感染的类型、分布及对常用药物的敏感程度,为临床提供及时合理的用药指导。方法选取2010年4月~2011年4月住院的145例病人的送检培养物,参照《全国临床检验操作规程》,自制普通培养基,采用ATB-expression细菌分析仪进行鉴定及药敏试验。结果 145株酵母样真菌中,白色念珠菌占66.2%,光滑念珠菌占15.2%,热带念珠菌占9.7%,近平滑念珠菌占3.4%,克柔念珠菌占2.0%,其他酵母样真菌占3.4%。药物敏感率为:5-氟胞嘧啶为96.6%,两性霉素B 100.0%,氟康唑71.0%,伊曲康唑64.8%,氟立康唑89.0%。结论呼伦贝尔地区真菌感染以白色念珠菌为主,感染人群多为老年人。氟康唑和伊曲康唑耐药率高于其他药物。临床工作中必须重视真菌的培养鉴定及用药规则。
Objective To understand the type of fungal infection Hulunbeier region,distribution and degree of sensitivity to commonly used drugs for labor to provide timely and reasonable medication guide.Methods According to National Clinical Laboratory Operating Procedures and ordinary culture medium,the bacterial identification and susceptibility testing were measured with instrument ATB-expression analyser.Results Of 145 yeast-like fungi,the constituent ratio of Candida albicans,Candida glabrata,Candida tropicalis,Candida parapsilosis and other yeast-like fungi were 66.2%,15.2%,9.7%,3.4%,2.0% and 3.4%,respectively.The sensitivity rate of fluorocytosine,amphotericin B,fluconazole,itraconazole and voriconazole were 96.6%,100%,71.0%,64.8% of and 89.0%.Conclusion The fungal infection in Hulunbeier region is mainly with Candida albicans.The resistance rate of fluconazole and itraconazole were higher than that of other drugs.
出处
《西部医学》
2012年第9期1797-1798,共2页
Medical Journal of West China
关键词
酵母样真菌
培养鉴定
药敏试验
Yeast-like fungus
Culture and identification
Drug sensitivity test