摘要
目的探讨妇科肿瘤术后静脉血栓(venous thromboembolism,VTE)的发生率、危险因素、临床特点、诊治及预防。方法回顾性分析收治的142例妇科恶性肿瘤患者,分析术后发生下肢静脉血栓患者的发生率、危险因素、临床特点、诊断及预防治疗。结果 142例妇科肿瘤术后患者静脉血栓的发生率7.04%(10/142),包括下肢静脉血栓9例和肺栓塞1例。其中宫颈癌术后发生率为6.94%(5/72);卵巢癌术后发生率10.71%(3/28);子宫内膜癌术后发生率4.76%(2/42)。患者多表现为下肢肿胀、疼痛、增粗;高龄、合并内科疾病、术中用血、手术时间、麻醉时间、肥胖等均增加血栓形成的风险;治疗采用以抗凝为主的综合性药物治疗。结论高龄、合并内科疾病、术中用血、手术时间、麻醉时间、肥胖等可能是血栓形成的高危因素;临床以左下肢静脉血栓为主。多采用彩色多普勒超声联合D-二聚体确诊VTE,积极预防、早期诊断和抗凝治疗对VTE有较好的疗效。
Objective To investigate the incidence, the risk factor, the clinical characteristics, the diagnosis, treatment and prevention of venous thromboembolism after surgery for gynecological cancers. Methods Clinical data of 142 patients with gynecologic malignant tumors were retrospectively. Results The incidence of postoperative venous thromboembolism was 7.04% for all the patients, including 6.94% for cervical cancer, 10.71% for ovarian cancer and 4.76% for endometrial cancer. The main feature was left lower limb swelling, pain, thickening in the patients with VTE. Advanced age, complications, blood transfusion, operation time, anesthesia time, fatness were risk factors for VTE. Anticoagulation was effective in the treatment of VTE. Conclusion Advanced age, complica- tions, blood transfusion, operation time, anesthesia time, fatness may be risk factors for VTE. VTE often occurred in the left lower limb. Combination of plasma D-dimmer and Doppler uhrasonography is the best choice to definitely diagnose the VTE. Active prevention, early diagnosis and anticoagulation are effective measures for the patients with VTE.
出处
《山西医科大学学报》
CAS
2012年第9期693-695,共3页
Journal of Shanxi Medical University
关键词
妇科肿瘤
静脉血栓
预防
gynecological cancer
venous thrombosis
prevention
